Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 10/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3492292 | 0.86 | BACE1 (0.41) | BACE1CTSDHTT | |
| SCHEMBL3492290 | 0.86 | BACE1 (0.41) | BACE1CTSDHTT | |
| SCHEMBL3490665 | 0.85 | BACE1 (0.54) | BACE1BCHECTSD | |
| SCHEMBL3490666 | 0.85 | BACE1 (0.54) | BACE1BCHECTSD | |
| SCHEMBL3491085 | 0.84 | BACE1 (0.40) | BACE1CTSD | |
| SCHEMBL3491089 | 0.84 | BACE1 (0.40) | BACE1CTSD | |
| SCHEMBL3491446 | 0.79 | BACE1 (0.50) | BACE1CTSD | |
| SCHEMBL3491449 | 0.79 | BACE1 (0.50) | BACE1CTSD | |
| SCHEMBL3493091 | 0.79 | BACE1 (0.43) | BACE1CTSD | |
| SCHEMBL3493086 | 0.79 | BACE1 (0.43) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589094-B2 | N- (3-amino-2-hydroxy-propyl) substituted alkylamide compounds | ELAN PHARMACEUTICALS, INC. (US) | 2009-09-15 | — | — | US | claimed |