⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620964 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1190430 | 0.97 | — | — | |
| SCHEMBL2760285 | 0.90 | — | — | |
| SCHEMBL18072564 | 0.88 | SOS1 (0.34) | — | |
| SCHEMBL20706020 | 0.88 | SOS1 (0.34) | — | |
| SCHEMBL17067231 | 0.88 | SOS1 (0.34) | — | |
| SCHEMBL1665473 | 0.88 | — | — | |
| SCHEMBL17067163 | 0.88 | SOS1 (0.34) | — | |
| SCHEMBL16070318 | 0.88 | — | — | |
| SCHEMBL17067233 | 0.88 | SOS1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260137650-A1 | MODULATORS OF RAR RELATED ORPHAN RECEPTORS (RORs) | 11949098 CANADA INC (CA) | 2026-05-21 | — | — | US | claimed |
| EP-4709383-A1 | INVERSE AGONISTS OF RAR RELATED ORPHAN RECEPTORS (RORS) | 11949098 Canada Inc. (CA) | 2026-03-18 | — | — | EP | claimed |
| WO-2025097247-A1 | METHOD OF TREATMENT OF FIBROSIS WITH INVERSE AGONIST OF RAR RELATED ORPHAN RECEPTORS (RORS) | 11949098 CANADA INC. (CA) | 2025-05-15 | — | — | WO | claimed |
| CN-119433616-A | Preparation and application of polybenzimidazole anion exchange membrane capable of regulating hydrophilic and hydrophobic side chains | 西南科技大学 | 2025-02-14 | — | — | CN | claimed |
| WO-2024229569-A9 | INVERSE AGONISTS OF RAR RELATED ORPHAN RECEPTORS (RORS) | 11949098 CANADA INC. (CA) | 2025-01-30 | — | — | WO | claimed |
| WO-2024229569-A1 | INVERSE AGONISTS OF RAR RELATED ORPHAN RECEPTORS (RORS) | 11949098 CANADA INC. (CA) | 2024-11-14 | — | — | WO | claimed |
| CN-118496619-A | Preparation method and application of quaternized polyether-ether-ketone anion exchange membrane | 西南科技大学 | 2024-08-16 | — | — | CN | claimed |
| US-20220000864-A1 | MODULATORS OF RAR-RELATED ORPHAN RECEPTORS (RORs) | 11949098 CANADA INC. (CA) | 2022-01-06 | — | — | US | claimed |
| EP-3883929-A1 | 4,5,6,7-TETRAHYDRO-L-BENZOTHIOPHENE MODULATORS OF RETINOIC ACID RECEPTOR RELATED (RAR) ORPHAN NUCLEAR RECEPTORS (RORS) | 11949098 Canada Inc. (CA) | 2021-09-29 | — | — | EP | claimed |
| CN-113166130-A | 4,5,6, 7-tetrahydro-L-benzothiophene modulators of retinoic acid receptor-associated (RAR) orphan nuclear receptors (ROR) | 11949098加拿大股份有限公司 | 2021-07-23 | — | — | CN | claimed |
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | claimed |
| WO-2008032064-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | WO | claimed |
| WO-2008032086-A1 | 2-BENZIMIDAZOLYL-6-MORPHOLINO-4-PHENYLPYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | WO | claimed |
| WO-2005105777-A1 | SUBSTITUTED THIOPHENE AMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-11-10 | — | — | WO | claimed |
| US-6169180-B1 | NEW ECONOMICAL AND SIMPLE PROCESS, USING NEW INTERMEDIATE COMPOUND, FOR THE PRODUCTION OF 3'-SUBSTITUTED 7-AMINO-3-PROPENYL-4-CEPHEM-CARBOXYLIC ACID DERIVATIVES | BIOCHEMIE GESELLSCHAFT (AT) | 2001-01-02 | — | — | US | claimed |
| US-5644052-A | MULTISTAGE REACTION TO PRODUCE CEPHALOSPORINS AND CHEMICAL INTERMEDIATES | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1997-07-01 | — | — | US | claimed |
| EP-0449191-B1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5438054-A | Antibacterial agent | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-01 | — | — | US | claimed |
| WO-1991014687-A1 | 2-(SUBSTITUTED PYRROLIDINYLTHIO)CARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-03 | — | — | WO | claimed |
| EP-0449191-A1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-10-02 | — | — | EP | claimed |