Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL27747304 | 1.00 | FFAR4 (0.56) | FFAR4FFAR1CYP1A2CYP3A4CYP2C19 | |
| Palmitic Acid SCHEMBL6850060 | 0.97 | FFAR4 (0.61) | FFAR4FFAR1CYP1A2CYP3A4CYP2C19 | |
| Stearic Acid SCHEMBL6846092 | 0.97 | FFAR4 (0.61) | FFAR4FFAR1CYP1A2CYP3A4CYP2C19 | |
| Adipic Acid SCHEMBL27729346 | 0.94 | FFAR4 (0.50) | FFAR4FFAR1CYP1A2CYP3A4CYP2C19 | |
| Myristic Acid SCHEMBL9615278 | 0.94 | FFAR4 (0.66) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL36574 | 0.89 | FFAR4 (0.51) | FFAR4FFAR1GPR84TSHRPTPN1 | |
| Acetic Acid SCHEMBL1982637 | 0.89 | CYP1A2 (0.48) | FFAR4FFAR1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9629705 | 0.87 | FFAR4 (0.53) | FFAR4FFAR1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1266266 | 0.87 | USP2 (0.55) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL27973903 | 0.87 | USP2 (0.55) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9879503-B2 | Methods of treating long-interval and high-contrast permeability subterranean formations with diverting fluids | HALLIBURTON ENERGY SERVICES, INC. (US) | 2018-01-30 | — | — | US | claimed |
| US-9702238-B2 | Wellbore servicing methods and compositions comprising degradable polymers | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-07-11 | — | — | US | claimed |
| US-20160304773-A1 | WELLBORE SERVICING METHODS AND COMPOSITIONS COMPRISING DEGRADABLE POLYMERS | HALLIBURTON ENERGY SERVICES, INC. | 2016-10-20 | — | — | US | claimed |
| EP-2748275-B1 | METHODS OF FLUID LOSS CONTROL, DIVERSION, AND SEALING USING DEFORMABLE PARTICULATES | HALLIBURTON ENERGY SERVICES INC (US) | 2016-09-28 | — | — | EP | claimed |
| US-9279077-B2 | Methods of forming and placing proppant pillars into a subterranean formation | HALLIBURTON ENERGY SERVICES, INC. (US) | 2016-03-08 | — | — | US | claimed |
| US-9200148-B2 | Controlled degradation fibers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-12-01 | — | — | US | claimed |
| EP-2943551-A1 | WELLBORE SERVICING METHODS AND COMPOSITIONS COMPRISING DEGRADABLE POLYMERS | Halliburton Energy Services, Inc. (US) | 2015-11-18 | — | — | EP | claimed |
| EP-2912138-A1 | WELLBORE SERVICING METHODS AND COMPOSITIONS COMPRISING DEGRADABLE POLYMERS | Halliburton Energy Services, Inc. (US) | 2015-09-02 | — | — | EP | claimed |
| EP-2421930-B1 | METHODS AND COMPOSITION RELATING TO THE CHEMICAL DEGRADATION OF DEGRADABLE POLYMERS | HALLIBURTON ENERGY SERVICES INC (US) | 2015-08-12 | — | — | EP | claimed |
| WO-2015065575-A1 | WELLBORE SERVICING METHODS AND COMPOSITIONS COMPRISING DEGRADABLE POLYMERS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2015-05-07 | — | — | WO | claimed |
| US-20080026959-A1 | Degradable particulates and associated methods | HALLIBURTON ENERGY SERVICES, INC. | 2008-01-31 | — | — | US | claimed |
| US-20080026960-A1 | Degradable particulates and associated methods | HALLIBURTON ENERGY SERVICES, INC. | 2008-01-31 | — | — | US | claimed |
| US-7216705-B2 | Methods of placing treatment chemicals | HALLIBURTON ENERGY SERVICES, INC. (US) | 2007-05-15 | — | — | US | claimed |
| US-20070078063-A1 | Subterranean treatment fluids and methods of treating subterranean formations | HALLIBURTON ENERGY SERVICES, INC. | 2007-04-05 | — | — | US | claimed |
| WO-2006131691-A1 | METHODS OF CONTROLLING THE DEGRADATION RATE OF HYDROLYTICALLY DEGRADABLE MATERIALS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2006-12-14 | — | — | WO | claimed |
| US-20060276345-A1 | Methods controlling the degradation rate of hydrolytically degradable materials | HALLIBURTON ENERGY SERVICERS, INC. | 2006-12-07 | — | — | US | claimed |
| US-20060185847-A1 | Methods of placing treatment chemicals | HALLIBURTON ENERGY SERVICES, INC. | 2006-08-24 | — | — | US | claimed |
| US-7093664-B2 | One-time use composite tool formed of fibers and a biodegradable resin | HALLIBURTON ENERGY SERVICES, INC. (US) | 2006-08-22 | — | — | US | claimed |
| US-20050205265-A1 | One-time use composite tool formed of fibers and a biodegradable resin | HALLIBURTON EENRGY SERVICES, INC. | 2005-09-22 | — | — | US | claimed |
| US-20050034861-A1 | On-the fly coating of acid-releasing degradable material onto a particulate | HALLIBURTON ENERGY SERVICES, INC. | 2005-02-17 | — | — | US | claimed |