⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL651148 | 0.84 | — | — | |
| SCHEMBL144303 | 0.83 | STAT3 (0.32) | — | |
| SCHEMBL142418 | 0.83 | STAT3 (0.32) | — | |
| SCHEMBL1327200 | 0.81 | — | — | |
| SCHEMBL1327578 | 0.79 | — | — | |
| SCHEMBL2081002 | 0.76 | PPM1D (0.32) | — | |
| SCHEMBL4474057 | 0.74 | PPM1D (0.32) | — | |
| SCHEMBL6052845 | 0.74 | PPM1D (0.34) | — | |
| SCHEMBL4370217 | 0.72 | PPM1D (0.33) | — | |
| SCHEMBL6052834 | 0.72 | PPM1D (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625909-B2 | Substituted quinazolinone compounds | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2009-12-01 | — | — | US | disclosed |
| US-7368453-B2 | Quinazolinone compounds with reduced bioaccumulation | CHIRON CORPORATION (US) | 2008-05-06 | — | — | US | disclosed |
| US-20050192297-A1 | Quinazolinone compounds with reduced bioaccumulation | CHIRON CORPORATION GLAXOSMITHKLINE | 2005-09-01 | — | — | US | disclosed |