Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.84 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330793 | 0.93 | PDE4B (0.87) | PDE4BNR3C1PDE4D | |
| SCHEMBL4338662 | 0.92 | PDE4B (0.85) | PDE4BNR3C1PDE4D | |
| SCHEMBL4336911 | 0.92 | PDE4B (0.85) | PDE4BNR3C1PDE4D | |
| SCHEMBL4336285 | 0.92 | PDE4B (0.85) | PDE4BNR3C1PDE4D | |
| SCHEMBL4340499 | 0.91 | PDE4B (0.84) | PDE4BNR3C1PDE4D | |
| SCHEMBL4330617 | 0.91 | PDE4B (0.84) | PDE4BNR3C1PDE4D | |
| SCHEMBL4334268 | 0.91 | PDE4B (0.84) | PDE4BNR3C1PDE4D | |
| SCHEMBL4339584 | 0.91 | PDE4B (0.84) | PDE4BNR3C1PDE4D | |
| SCHEMBL4343356 | 0.91 | PDE4B (1.00) | PDE4BPDE4D | |
| SCHEMBL5962657 | 0.91 | PDE4B (0.85) | PDE4BNR3C1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539753-B1 | PYRAZOLO(3,4-B)PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LTD (GB) | 2009-09-09 | — | — | EP | claimed |