SCHEMBL4468331

SCHEMBL4468331

C=C[CH][SiH2]CC=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL367608 0.72
SCHEMBL3762765 0.65
SCHEMBL5495270 0.63
SCHEMBL170292 0.62
SCHEMBL236908 0.61
SCHEMBL68490 0.57
SCHEMBL4533037 0.57
SCHEMBL6293076 0.57
SCHEMBL588334 0.57
SCHEMBL250606 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7598307-B2 Transparent masterbatches for thermoplastics DEGUSSA AG (DE) 2009-10-06 US disclosed
US-20070072972-A1 Transparent masterbatches for thermoplastics DEGUSSA AG (DE) 2007-03-29 US disclosed
EP-1295890-B1 Novel pyrazine derivatives or salts thereof, pharmaceutical composition containing the same, and production intermediates thereof TOYAMA CHEMICAL CO LTD (JP) 2005-04-27 EP disclosed
EP-1256588-B1 NOVEL PYRAZINE DERIVATIVES OR SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THE DERIVATIVES OR THE SALTS AND INTERMEDIATES FOR THE PREPARATION OF BOTH TOYAMA CHEMICAL CO LTD (JP) 2005-02-02 EP disclosed
US-6800629-B2 VIRICIDES TOYAMA CHEMICAL CO., LTD. (JP) 2004-10-05 US disclosed
US-20030130213-A1 Novel pyrazine derivatives or salts thereof, pharmaceutical composition containing the same, and production intermediates thereof TOYAMA CHEMICAL CO., LTD. (JP) 2003-07-10 US disclosed
EP-1295890-A1 Novel pyrazine derivatives or salts thereof, pharmaceutical composition containing the same, and production intermediates thereof TOYAMA CHEMICAL CO., LTD. (JP) 2003-03-26 EP disclosed
EP-1256588-A1 NOVEL PYRAZINE DERIVATIVES OR SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THE DERIVATIVES OR THE SALTS AND INTERMEDIATES FOR THE PREPARATION OF BOTH TOYAMA CHEMICAL CO., LTD. (JP) 2002-11-13 EP disclosed