Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13920968 | 0.84 | MAPK14 (0.60) | MAPK14CCNA2CDK2CSNK1ECDK5 | |
| SCHEMBL14561003 | 0.82 | — | — | |
| SCHEMBL4476329 | 0.82 | MAPK14 (0.57) | MAPK14CCNA2CDK2CSNK1ECDK5 | |
| SCHEMBL4471008 | 0.79 | MAPK14 (0.60) | MAPK14CCNA2CDK2CSNK1ECDK5 | |
| SCHEMBL14561793 | 0.76 | — | — | |
| SCHEMBL14560997 | 0.75 | — | — | |
| SCHEMBL3520464 | 0.75 | CDK2 (0.67) | MAPK14CCNA2CDK2CSNK1ECDK5 | |
| SCHEMBL4471049 | 0.74 | — | — | |
| SCHEMBL4458202 | 0.74 | MAPK14 (0.58) | MAPK14CCNA2CDK2CSNK1ECDK5 | |
| SCHEMBL14561548 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504501-B2 | Antiprotozoal imidazopyridine compounds | MERIAL LIMITED (US) | 2009-03-17 | — | — | US | disclosed |
| US-7504501-B2 | Antiprotozoal imidazopyridine compounds | MERIAL LIMITED (US) | 2009-03-17 | — | — | US | disclosed |