Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 18/20 | 0.80 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4472908 | 0.93 | HRH3 (0.73) | HRH3KCNH2ADRA1A | |
| SCHEMBL4473975 | 0.90 | HRH3 (0.98) | HRH3KCNH2ADRA1A | |
| SCHEMBL502186 | 0.89 | HRH3 (1.00) | HRH3KCNH2ADRA1A | |
| SCHEMBL4476306 | 0.89 | HRH3 (0.98) | HRH3KCNH2ADRA1A | |
| SCHEMBL4484953 | 0.89 | HRH3 (0.80) | HRH3KCNH2ADRA1A | |
| SCHEMBL502291 | 0.89 | HRH3 (0.98) | HRH3KCNH2ADRA1A | |
| SCHEMBL4464034 | 0.89 | HRH3 (0.98) | HRH3KCNH2ADRA1A | |
| SCHEMBL4474087 | 0.88 | HRH3 (0.98) | HRH3KCNH2ADRA1A | |
| SCHEMBL4481578 | 0.88 | HRH3 (0.98) | HRH3KCNH2ADRA1A | |
| SCHEMBL4469934 | 0.87 | HRH3 (0.82) | HRH3KCNH2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1717230-B1 | FUSED-RING 4-OXOPYRIMIDINE DERIVATIVE | MSD KK (JP) | 2014-08-06 | — | — | EP | claimed |
| US-7521455-B2 | Fused ring 4-oxopyrimidine derivative | BANYU PHARMACEUTICAL CO. LTD. (JP) | 2009-04-21 | — | — | US | claimed |