Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.61 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.61 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.61 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4470243 | 1.00 | KDM4E (0.62) | KDM4EHTTAGTR1AGTR2GRM2 | |
| SCHEMBL4472255 | 0.83 | KDM4E (0.60) | KDM4EHTTAGTR1AGTR2GRM2 | |
| SCHEMBL4489207 | 0.81 | CNR2 (0.58) | KDM4EHTTAGTR1AGTR2GRM2 | |
| SCHEMBL9163572 | 0.81 | CNR2 (0.58) | KDM4EHTTAGTR1AGTR2GRM2 | |
| SCHEMBL9163565 | 0.81 | CNR2 (0.58) | KDM4EHTTAGTR1AGTR2GRM2 | |
| SCHEMBL9163766 | 0.81 | CNR2 (0.58) | KDM4EHTTAGTR1AGTR2GRM2 | |
| SCHEMBL70870 | 0.80 | KDM4E (0.65) | KDM4EHTTAGTR1AGTR2CYP2A13 | |
| SCHEMBL1591329 | 0.80 | KDM4E (0.65) | KDM4EHTTAGTR1AGTR2CYP2A13 | |
| SCHEMBL1591865 | 0.80 | KDM4E (0.65) | KDM4EHTTAGTR1AGTR2CYP2A13 | |
| SCHEMBL4510409 | 0.80 | KDM4E (0.65) | KDM4EHTTAGTR1AGTR2CYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595397-B2 | Compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-29 | — | — | US | disclosed |
| EP-1966132-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-10 | — | — | EP | disclosed |
| US-20070191340-A1 | Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-16 | — | — | US | disclosed |
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191340-A1 | Compounds Which Modulate The CB2 Receptor | CNR1, CNR2, ARRB1 | KDM4E 2472/4885HTT 3858/4885AGTR1 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.