Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26448424 | 0.83 | MAPT (0.49) | ALDH1A1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL23462185 | 0.83 | TSHR (0.50) | ALDH1A1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL8629493 | 0.81 | TSHR (0.48) | ALDH1A1MAPTSMN1; SMN2LMNATSHR | |
| SCHEMBL10849451 | 0.81 | MAPK1 (0.49) | ALDH1A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL10389513 | 0.81 | NPC1 (0.53) | ALDH1A1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL11264199 | 0.81 | CYP3A4 (0.53) | ALDH1A1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL19834811 | 0.80 | TSHR (0.47) | ALDH1A1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL11717329 | 0.80 | TSHR (0.47) | ALDH1A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL3179093 | 0.80 | MAPT (0.61) | ALDH1A1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL13365129 | 0.79 | CYP4F2 (0.48) | ALDH1A1MAPTLMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006149-B1 | PROCESS FOR THE PREPARATION OF ALKYL ESTERS OF 2,5-DIMETHYLFURAN-3-CARBOXYLIC ACID | BASF Aktiengesellschaft (DE) | 1982-01-06 | — | — | EP | claimed |
| US-4207243-A | Preparation of 2,5-dimethylfuran-3-carboxylic acid alkyl esters | BASF AKTIENGESELLSCHAFT (DE) | 1980-06-10 | — | — | US | claimed |
| JP-9255675-A | — | — | None | — | — | JP | disclosed |
| JP-11060569-A | — | — | None | — | — | JP | disclosed |
| WO-2010059393-A1 | SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-27 | — | — | WO | disclosed |
| US-7608727-B2 | Process for the preparation of furan compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2009-10-27 | — | — | US | disclosed |
| EP-1826202-A1 | Process for the preparation of furan compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-08-29 | — | — | EP | disclosed |
| US-20070197806-A1 | Process for the preparation of furan compounds | DAICEL CHEMICAL INDUSTRIES, LTD. | 2007-08-23 | — | — | US | disclosed |
| US-6506913-B2 | Wood preservatives | SANKYO COMPANY, LIMITED (JP) | 2003-01-14 | — | — | US | disclosed |
| US-20020091154-A1 | Dimethylfurancarboxyanilide derivatives | SANKYO COMPANY LIMITED (JP) | 2002-07-11 | — | — | US | disclosed |
| US-6380247-B2 | A WOOD PRESERVATIVE; POTENTIATION WHEN MIXED WITH AT LEAST ONE OF 3-BROMO-2,3-DIIODO-2-PROPENYL-ETHYLCARBAMATE, 3-IODO-2-PROPYNYLBUTYL-CARBAMATE AND 4-CHLOROPHENYL-3-IODOPROPARGYLFORMAL; MICROBIOCIDES | SANKYO COMPANY, LIMITED (JP) | 2002-04-30 | — | — | US | disclosed |
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |
| EP-0852498-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| JP-H09255675-A | PRODUCTION OF FURAN-3-CARBOXYAMIDE DERIVATIVE | DAICEL CHEM IND LTD | 1997-09-30 | — | — | JP | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |
| EP-0755927-A1 | DIMETHYLFURANCARBOXANILIDE DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |
| US-4207243-A | Preparation of 2,5-dimethylfuran-3-carboxylic acid alkyl esters | BASF AKTIENGESELLSCHAFT (DE) | 1980-06-10 | — | — | US | disclosed |
| US-4201715-A | Process for the anilidization of carboxylic acid esters | WACKER-CHEMIE GMBH (DE) | 1980-05-06 | — | — | US | disclosed |
| US-4025537-A | Preparation of 3-carboalkoxy or 3-alkanoyl furans | KRETCHMER RICHARD ALLAN | 1977-05-24 | — | — | US | disclosed |
| US-3980675-A | HYDROLYSIS OF A DIACETYL DIMER IN AN ACID CATALYST | MONTEDISON S.P.A. (IT) | 1976-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197806-A1 | Process for the preparation of furan compounds | CBR1, CBR3, POR | ALDH1A1 160/4885MAPT 4084/4885SMN1; SMN2 3095/4885 |
| US-20020091154-A1 | Dimethylfurancarboxyanilide derivatives | C9, CBR1, CBR3 | ALDH1A1 116/4885MAPT 3855/4885SMN1; SMN2 2164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.