⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4471331 | 1.00 | — | — | |
| SCHEMBL29391624 | 0.78 | KMT2A (0.76) | — | |
| SCHEMBL221242 | 0.78 | KMT2A (0.76) | — | |
| SCHEMBL10405315 | 0.78 | MEN1 (0.61) | — | |
| SCHEMBL30947359 | 0.76 | KMT2A (0.73) | — | |
| SCHEMBL6574416 | 0.76 | KMT2A (0.73) | — | |
| SCHEMBL6175584 | 0.76 | KMT2A (0.73) | — | |
| Bromide SCHEMBL28368455 | 0.76 | KMT2A (0.73) | — | |
| SCHEMBL4243882 | 0.76 | KMT2A (0.73) | — | |
| SCHEMBL11133606 | 0.76 | KMT2A (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086952-A2 | COMPOSITIONS FOR THE TREATMENT OF DEGENERATIVE ARTICULAR DISEASES | PROJECH SCIENCE TO TECHNOLOGY, S.L. (ES) | 2009-07-16 | — | — | WO | claimed |
| WO-2009086952-A2 | COMPOSITIONS FOR THE TREATMENT OF DEGENERATIVE ARTICULAR DISEASES | PROJECH SCIENCE TO TECHNOLOGY, S.L. (ES) | 2009-07-16 | — | — | WO | disclosed |
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | disclosed |
| EP-0762883-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033466-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1995-12-14 | — | — | WO | disclosed |