⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567891 | 0.63 | — | — | |
| SCHEMBL4835827 | 0.62 | — | — | |
| SCHEMBL8813437 | 0.57 | — | — | |
| SCHEMBL16289840 | 0.57 | — | — | |
| SCHEMBL169196 | 0.53 | — | — | |
| SCHEMBL2873164 | 0.48 | — | — | |
| SCHEMBL1173857 | 0.42 | — | — | |
| SCHEMBL31070934 | 0.42 | — | — | |
| SCHEMBL19086068 | 0.38 | — | — | |
| Benzene SCHEMBL1951518 | 0.35 | TP53 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067629-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2024-02-29 | — | — | US | disclosed |
| US-11753399-B2 | Therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2023-09-12 | — | — | US | disclosed |
| EP-3752495-B1 | PYRIDINE DERIVATIVES AND THEIR USE FOR TREATING HIV INFECTION | GILEAD SCIENCES INC (US) | 2023-07-19 | — | — | EP | disclosed |
| CN-111836805-B | Pyridine derivatives and their use for the treatment of HIV infection | 吉利德科学公司 | 2023-07-14 | — | — | CN | disclosed |
| US-11267801-B2 | Therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2022-03-08 | — | — | US | disclosed |
| EP-3954679-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HIV INFECTIONS | Gilead Sciences, Inc. (US) | 2022-02-16 | — | — | EP | disclosed |
| EP-3409667-B1 | AMIDE COMPOUNDS FOR THE TREATMENT OF HIV INFECTIONS | GILEAD SCIENCES INC (US) | 2021-07-21 | — | — | EP | disclosed |
| US-20210171498-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2021-06-10 | — | — | US | disclosed |
| US-20210009555-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2021-01-14 | — | — | US | disclosed |
| EP-3752495-A1 | PYRIDINE DERIVATIVES AND THEIR USE FOR TREATING HIV INFECTION | GILEAD SCIENCES, INC. (US) | 2020-12-23 | — | — | EP | disclosed |
| US-20030212116-A1 | Heterocyclic imino compounds and fungicides and insecticides for agricultural and horitcultural use | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-11-13 | — | — | US | disclosed |
| US-6500951-B1 | RING CLOSING A CARBOXYLIC ACID DERIVATIVE IN PRESENCE OF A NITROGEN CONTAINING AROMATIC COMPOUND AND A BORON COMPOUND; HIGH YIELD AND PURITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-31 | — | — | US | disclosed |
| EP-1243580-A1 | HETEROCYCLIC IMINO COMPOUNDS AND FUNGICIDES AND INSECTICIDES FOR AGRICULTURAL AND HORTICULTURAL USE | Nissan Chemical Industries, Ltd. (JP) | 2002-09-25 | — | — | EP | disclosed |
| CN-1334805-A | Process for preparing pyridazin-2-one derivs. | SUMITOMO CHEMICAL CO (JP) | 2002-02-06 | — | — | CN | disclosed |
| EP-1137641-A1 | PROCESS FOR PREPARING PYRIDAZIN-3-ON DERIVATIVES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034249-A1 | PROCESS FOR PREPARING PYRIDAZIN-3-ON DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-06-15 | — | — | WO | disclosed |
| EP-0373836-B1 | Improvements in or relating to serotonin and norepinephrine uptake inhibitors | LILLY CO ELI (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0373836-A1 | Improvements in or relating to serotonin and norepinephrine uptake inhibitors | ELI LILLY AND COMPANY (US) | 1990-06-20 | — | — | EP | disclosed |
| US-4902710-A | THIO-, SULFINYL-, OR SULFONYL-PROPANAMINES; ANTIDEPRESSANTS, ANXIOLYTIC AGENTS; NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| US-4515618-A | PLANT GROWTH REGULATORS | CHEVRON RESEARCH COMPANY (US) | 1985-05-07 | — | — | US | disclosed |