SCHEMBL4472439

SCHEMBL4472439

COc1cc(C)c(O)c(OC)c1OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.57
CYP3A4 P08684 1/20 0.54
MAPT P10636 1/20 0.54
ACHE P22303 1/20 0.50
TUBB4A P04350 1/20 0.45
TUBB P07437 1/20 0.45
TUBA3C P0DPH7 1/20 0.45
TUBA1B P68363 1/20 0.45
TUBA4A P68366 1/20 0.45
TUBB4B P68371 1/20 0.45
TUBB3 Q13509 1/20 0.45
TUBB2A Q13885 1/20 0.45
TUBB8 Q3ZCM7 1/20 0.45
TUBA3E Q6PEY2 1/20 0.45
TUBA1A Q71U36 1/20 0.45
TUBA1C Q9BQE3 1/20 0.45
TUBB6 Q9BUF5 1/20 0.45
TUBB2B Q9BVA1 1/20 0.45
TUBB1 Q9H4B7 1/20 0.45
TDP1 Q9NUW8 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29421891 1.00 EPHX2 (0.57) EPHX2CYP3A4MAPTACHETUBB4A
SCHEMBL1808984 0.86 EPHX2 (0.49) EPHX2CYP3A4MAPTACHETDP1
SCHEMBL4127825 0.86 MAPT (0.54) EPHX2CYP3A4MAPTACHETUBB4A
SCHEMBL5587869 0.84 MAPT (0.56) CYP3A4MAPTACHETUBB4ATUBB
Benzene SCHEMBL28616661 0.83 EPHX2 (0.46) EPHX2CYP3A4MAPTACHETDP1
SCHEMBL11333975 0.82 EPHX2 (0.43) EPHX2CYP3A4MAPTACHETUBB4A
SCHEMBL3678118 0.82 MAPT (0.48) EPHX2CYP3A4MAPTACHETDP1
SCHEMBL27553867 0.81 MAPT (0.58) EPHX2CYP3A4MAPTACHETDP1
SCHEMBL20123234 0.81 TDP1 (0.48) EPHX2CYP3A4MAPTACHETDP1
SCHEMBL12587650 0.80 MAPT (0.52) EPHX2CYP3A4MAPTACHETUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181047-A Method for preparing biphenol from cresol 中国科学院大连化学物理研究所 2022-03-15 CN claimed
CN-109276563-B Application of pharmaceutical composition in preparing medicine for treating or preventing individual infection virus 珠海市鑫展生物科技有限公司 2021-04-09 CN claimed
CN-105567923-A Rubber lining processing method of metal valve plate of soft sealing valve ANHUI TONGLING KELI VALVE CO LTD 2016-05-11 CN claimed
CN-105567915-A Heat treatment method of valve plate sealing face ANHUI TONGLING KELI VALVE CO LTD 2016-05-11 CN claimed
EP-1915333-B1 PROCESS FOR THE PREPARATION OF UBIHYDROQUINONES AND UBIQUINONES DSM IP ASSETS BV (NL) 2015-06-03 EP claimed
CN-102775290-A Preparation method of 2-(chloromethyl)-5,6-dimethoxy-3-methyl-1,4-para benzoquinone UNIV KUNMING SCIENCE & TECHNOLOGY 2012-11-14 CN claimed
CN-101243031-B Process for preparing ubiquinones and ubiquinones DSM IP ASSETS BV 2012-05-09 CN claimed
CN-1800131-B 2,3,4,5-tetramethoxyl toluene synthesis method JIANGSU YABANG PHARMACEUTICAL RES & DEV CO LTD 2011-01-05 CN claimed
US-7601877-B2 Condensation of a prenol or isoprenol with a hydroquinone or derivative in the presence of 0.005-1.0 mol percent of a Bronsted or Lewis acid catalyst selected from a bismuth, indium or Group 3 chloride, a heteropolyacid, and an NH- or a CH-acidic compound, oxidizing the ubihydroquinone; improved kinetics DSM IP ASSETS B.V. (NL) 2009-10-13 US claimed
US-20080275275-A1 Process for the Preparation of Ubihydroquinones and Ubiquinones DSM IPASSETS B.V. (NL) 2008-11-06 US claimed
CN-101243031-A Process for the preparation of ubihydroquinones and ubiquinones DSM IP ASSETS BV (NL) 2008-08-13 CN claimed
EP-1915333-A1 PROCESS FOR THE PREPARATION OF UBIHYDROQUINONES AND UBIQUINONES DSMIP Assets B.V. (NL) 2008-04-30 EP claimed
WO-2007017168-A1 PROCESS FOR THE PREPARATION OF UBIHYDROQUINONES AND UBIQUINONES DSM IP ASSETS B.V. (NL) 2007-02-15 WO claimed
CN-1800131-A 2,3,4,5-tetramethoxyl toluene synthesis method JIANGSU YABANG PHARMACEUTICAL (CN) 2006-07-12 CN claimed
US-4163864-A Process for preparing 2-methyl-3-prenyl-4,5,6-trimethoxyphenol EISAI CO., LTD. (JP) 1979-08-07 US claimed
US-4062879-A Process for synthesis of coenzyme Q compounds EISAI CO., LTD. (JA) 1977-12-13 US claimed
US-4061660-A Process for synthesis of coenzyme Q compounds EISAI CO., LTD. (JA) 1977-12-06 US claimed
JP-52042837-A None JP disclosed
JP-S5242837-A SYNTHETIC PROCESS FOR COENZYME Q GROUP COMPOUNDS EISAI CO LTD 1977-04-04 JP disclosed
JP-S5242835-A PROCESS FOR PREPARATION OF 6-METHYL-2,3,4-TRIMETHOXYPHENOL EISAI CO LTD 1977-04-04 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080275275-A1 Process for the Preparation of Ubihydroquinones and Ubiquinones UBE2D3, UBE2L3, UBE2I EPHX2 328/4885CYP3A4 694/4885MAPT 2939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.