Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TET2 | Q6N021 | 6/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.42 |
| ▸ | TET3 | O43151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347615 | 0.94 | — | — | |
| SCHEMBL85839 | 0.94 | — | — | |
| SCHEMBL2650130 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL25302426 | 0.91 | — | — | |
| SCHEMBL9468720 | 0.91 | OR51E2 (0.50) | OR51E2SMN1; SMN2TET2GABRR1KDM4A | |
| Hydrochloric Acid SCHEMBL2436911 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL2651912 | 0.91 | — | — | |
| Oxalic Acid SCHEMBL27467363 | 0.88 | OR51E2 (0.48) | OR51E2SMN1; SMN2TET2GABRR1KDM4A | |
| Acetic Acid SCHEMBL3061328 | 0.86 | OR51E2 (0.46) | OR51E2SMN1; SMN2TET2GABRR1KDM4A | |
| Diaminopropanoic Acid SCHEMBL9219051 | 0.81 | PTGS1 (0.44) | OR51E2SMN1; SMN2TET2GABRR1KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503844-A | C-13 and C-7 site structure modified paclitaxel compound and preparing method thereof | UNIV SHANGHAI | 2016-04-20 | — | — | CN | claimed |
| CN-105294611-A | Side chain C-3 position-modified taxane analogs and preparation method thereof | UNIV SHANGHAI | 2016-02-03 | — | — | CN | claimed |
| CN-105503844-A | C-13 and C-7 site structure modified paclitaxel compound and preparing method thereof | UNIV SHANGHAI | 2016-04-20 | — | — | CN | disclosed |
| CN-105294611-A | Side chain C-3 position-modified taxane analogs and preparation method thereof | UNIV SHANGHAI | 2016-02-03 | — | — | CN | disclosed |
| CN-104693156-A | 9,10-dihydroxy-1-deoxy-taxol analogue and preparation method thereof | UNIV SHANGHAI | 2015-06-10 | — | — | CN | disclosed |
| CN-102363612-B | Method for extracting taxol simply, conveniently and efficiently | ZHAO HUA | 2013-06-19 | — | — | CN | disclosed |
| CN-102363612-A | Method for extracting taxol simply, conveniently and efficiently | HUA ZHAO | 2012-02-29 | — | — | CN | disclosed |
| US-7517858-B1 | Prodrugs of pharmaceuticals with improved bioavailability | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-14 | — | — | US | disclosed |
| EP-0837630-B1 | PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY | HOSTETLER KARL Y (US) | 2007-12-26 | — | — | EP | disclosed |
| CN-101081841-A | Novel 2'-alpha-hydroxyalkyl taxone compound and preparation method thereof | SHANGHAI INST MATERIA MEDICA (CN) | 2007-12-05 | — | — | CN | disclosed |
| EP-0837630-A4 | PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY | UNIV CALIFORNIA (US) | 1998-11-25 | — | — | EP | disclosed |
| US-5827831-A | Lipid nucleotide analog prodrugs for oral administration | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-10-27 | — | — | US | disclosed |
| EP-0837630-A1 | PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-04-29 | — | — | EP | disclosed |
| US-5744592-A | IMPROVING THE BIOAVAILABILITY AND ABSORPTION OF A DRUG THROUGH THE DIGESTIVE TRACT BY COVALENTLY BONDING THE DRUG AND A 1-O-OR-S-ALKYL-SN-GLYCERO-3-PHOSPHATE | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-04-28 | — | — | US | disclosed |
| WO-1996039831-A1 | PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5484809-A | ANTITUMOR | VESTAR, INC. (US) | 1996-01-16 | — | — | US | disclosed |
| US-5411947-A | converting drugs having suitable functional groups to 1-O-alkyl-, 1-O-acyl-, 1-S-acyl, and 1-S-alkyl-sn-glycero-3-phosphate derivatives; drugs such as AZT, cladribine, AICA-Riboside | VESTAR, INC. (US) | 1995-05-02 | — | — | US | disclosed |