Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 9/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.44 |
| ▸ | PDE4A | P27815 | 6/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3602184 | 0.91 | PDE4B (0.46) | PDE4BPDE4DPDE4APDE4CITGB1 | |
| SCHEMBL3600833 | 0.88 | PDE4B (0.44) | PDE4BPDE4DPDE4APDE4CMAPK1 | |
| SCHEMBL3607568 | 0.83 | PDE4B (0.51) | PDE4BPDE4DPDE4APDE4CITGB1 | |
| SCHEMBL3607635 | 0.83 | PDE4B (0.56) | PDE4BPDE4DPDE4APDE4CITGB1 | |
| SCHEMBL3611286 | 0.83 | MEN1 (0.52) | PDE4BPDE4DPDE4APDE4CITGB1 | |
| SCHEMBL3607400 | 0.82 | PDE4A (0.42) | PDE4BPDE4DPDE4APDE4CITGB1 | |
| SCHEMBL5793483 | 0.82 | PDE4B (0.43) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL3605765 | 0.82 | PDE4B (0.43) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL3599724 | 0.82 | PDE4D (0.45) | PDE4BPDE4DPDE4APDE4CITGB1 | |
| SCHEMBL3615527 | 0.81 | PDE4B (0.41) | PDE4BPDE4DPDE4APDE4CITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495017-B2 | Phosphodiesterase 4 inhibitors | MEMORY PHARMACEUTICALS CORPORATION (US) | 2009-02-24 | — | — | US | claimed |
| US-20070203197-A1 | Phosphodiesterase 4 inhibitors | HOPPER ALLEN | 2007-08-30 | — | — | US | claimed |
| US-7495017-B2 | Phosphodiesterase 4 inhibitors | MEMORY PHARMACEUTICALS CORPORATION (US) | 2009-02-24 | — | — | US | disclosed |
| US-20070203197-A1 | Phosphodiesterase 4 inhibitors | HOPPER ALLEN | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203197-A1 | Phosphodiesterase 4 inhibitors | PDE4A, PDE4B, PDE12 | PDE4B 2/4885PDE4D 6/4885PDE4A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.