Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 5/20 | 0.56 |
| ▸ | BID | P55957 | 4/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.56 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | EP300 | Q09472 | 2/20 | 0.56 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.56 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.56 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | F7 | P08709 | 3/20 | 0.49 |
| ▸ | F3 | P13726 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271367 | 0.98 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL5271556 | 0.98 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL6436997 | 0.98 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL6435534 | 0.98 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL28182972 | 0.98 | KAT8 (0.55) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL6434109 | 0.98 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL5272268 | 0.98 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL5273325 | 0.98 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL2821516 | 0.98 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL5274232 | 0.98 | KAT8 (0.59) | KAT8BIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130934-B | A kind of butylphenyl phthaleine bulk pharmaceutical chemicals product and preparation method thereof | 石药集团恩必普药业有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-107216298-B | Preparation method of butylphthalide | 北京科莱博医药开发有限责任公司 | 2020-01-31 | — | — | CN | disclosed |
| CN-105130934-B | A kind of butylphenyl phthaleine bulk pharmaceutical chemicals product and preparation method thereof | 石药集团恩必普药业有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-107216298-A | A kind of preparation method of butylphenyl phthaleine | 北京科莱博医药开发有限责任公司 | 2017-09-29 | — | — | CN | disclosed |
| CN-105517988-A | 5-bromine-2-([alpha]-hydroxypentyl)benzoic acid sodium salts in different crystal forms, and preparation method thereof | ZHEJIANG AUSUN PHARMACEUTICAL CO LTD | 2016-04-20 | — | — | CN | disclosed |
| EP-2048140-A1 | Deuterated chemiluminescent 1,2-dioxetanes | Giri, Brij P. (US) | 2009-04-15 | — | — | EP | disclosed |
| EP-1453822-A4 | DEUTERIUM-BASED CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2004-11-24 | — | — | EP | disclosed |
| EP-1453822-A2 | DEUTERIUM-BASED CHEMILUMINESCENT 1,2-DIOXETANES | Giri, Brij P. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003054506-A2 | DEUTERIUM-BASED CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ PAL (US) | 2003-07-03 | — | — | WO | disclosed |