SCHEMBL4473632

SCHEMBL4473632

CCC(C(=O)O)c1cccc(Cn2ccc(OCc3ccc(F)cc3F)c(Br)c2=O)c1

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 20/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5350329 0.86 MAPK14 (0.51) MAPK14
SCHEMBL4373903 0.84 MAPK14 (1.00) MAPK14
SCHEMBL4379196 0.83 MAPK14 (0.80) MAPK14
SCHEMBL4480503 0.81 MAPK14 (0.73) MAPK14
SCHEMBL4374142 0.81 MAPK14 (0.76) MAPK14
SCHEMBL4384993 0.81 MAPK14 (0.79) MAPK14
SCHEMBL4466555 0.81 MAPK14 (0.79) MAPK14
SCHEMBL4483003 0.81 MAPK14 (0.81) MAPK14
SCHEMBL4378307 0.80 MAPK14 (0.85) MAPK14
SCHEMBL4384848 0.80 MAPK14 (0.80) MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629363-B2 antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease PFIZER INC (US) 2009-12-08 US disclosed