Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 13/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.62 |
| ▸ | SCD | O00767 | 2/20 | 0.42 |
| ▸ | SNCA | P37840 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186359 | 0.88 | HDAC6 (0.64) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4294327 | 0.87 | HDAC2 (0.62) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4161740 | 0.82 | HDAC2 (0.74) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4170065 | 0.82 | HDAC4 (0.69) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4198413 | 0.79 | HDAC4 (0.71) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14164269 | 0.77 | HDAC2 (1.00) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4814015 | 0.77 | HDAC2 (0.69) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4191552 | 0.76 | HDAC3 (0.67) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5321500 | 0.74 | SCD (0.49) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4818519 | 0.74 | HRH3 (0.50) | HDAC2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009089598-A2 | MSMB-GENE METHYLATION BASED DIAGNOSIS, STAGING AND PROGNOSIS OF PROSTATE CANCER | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2009-07-23 | — | — | WO | disclosed |