SCHEMBL4475802

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4465624	0.91	CNR2 (0.52)	CNR2ROCK1FAAHKDM4EALDH1A1
	SCHEMBL4461898	0.91	CNR2 (0.52)	CNR2ROCK1FAAHKDM4EALDH1A1
	SCHEMBL4461902	0.91	CNR2 (0.52)	CNR2ROCK1FAAHKDM4EALDH1A1
	SCHEMBL4466286	0.89	ROCK1 (0.54)	CNR2ROCK1FAAHKDM4EMAPT
	SCHEMBL4466288	0.89	ROCK1 (0.54)	CNR2ROCK1FAAHKDM4EMAPT
	SCHEMBL4469872	0.89	ROCK1 (0.54)	CNR2ROCK1FAAHKDM4EMAPT
	SCHEMBL4470987	0.88	CNR2 (0.55)	CNR2ROCK1KDM4EALDH1A1CA1
	SCHEMBL4470982	0.88	CNR2 (0.55)	CNR2ROCK1KDM4EALDH1A1CA1
	SCHEMBL4478689	0.88	CNR2 (0.55)	CNR2ROCK1KDM4EALDH1A1CA1
	SCHEMBL4471995	0.87	CNR2 (0.56)	CNR2FAAHKDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.