Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464044 | 0.93 | ERBB2 (0.68) | ERBB2EGFR | |
| SCHEMBL4464003 | 0.86 | ERBB2 (0.55) | ERBB2EGFR | |
| SCHEMBL4468667 | 0.85 | ERBB2 (0.80) | ERBB2EGFR | |
| SCHEMBL4467738 | 0.83 | ERBB2 (0.84) | ERBB2 | |
| SCHEMBL4476374 | 0.79 | ERBB2 (0.79) | ERBB2EGFR | |
| SCHEMBL4466005 | 0.78 | ERBB2 (0.63) | ERBB2EGFR | |
| SCHEMBL4455092 | 0.78 | ERBB2 (0.52) | ERBB2EGFR | |
| SCHEMBL4465878 | 0.78 | ERBB2 (0.71) | ERBB2EGFR | |
| SCHEMBL4471215 | 0.77 | ERBB2 (0.84) | ERBB2 | |
| SCHEMBL4466009 | 0.77 | ERBB2 (0.79) | ERBB2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585869-B2 | Substituted heterocylces for the treatment of abnormal cell growth | PFIZER, INC. (US) | 2009-09-08 | — | — | US | claimed |