SCHEMBL4477147

SCHEMBL4477147

NC(CC(CO)C(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 6/20 1.00
SLC1A2 P43004 7/20 0.64
SLC1A3 P43003 5/20 0.64
GRIK1 P39086 10/20 0.59
GRIK2 Q13002 10/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7103579 1.00 SLC1A1 (1.00) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL9418943 0.84 SLC1A1 (0.70) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL6029513 0.81 SLC1A1 (0.68) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL6029508 0.81 SLC1A1 (0.68) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL5293587 0.80 SLC1A1 (0.67) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL5279387 0.79 SLC1A1 (0.65) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL5596021 0.79 SLC1A1 (0.65) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL13621431 0.78 SLC1A1 (0.64) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL3471272 0.78 SLC1A1 (0.64) SLC1A1SLC1A2SLC1A3GRIK1GRIK2
SCHEMBL3470567 0.78 SLC1A1 (0.64) SLC1A1SLC1A2SLC1A3GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101965397-B Transferases and oxidoreductases, nucleic acids encoding them, and methods for their preparation and use 巴斯夫酶有限责任公司 2016-09-28 CN disclosed
EP-2089529-A2 POLYPEPTIDES AND BIOSYNTHETIC PATHWAYS FOR THE PRODUCTION OF STEREOISOMERS OF MONATIN AND THEIR PRECURSORS Cargill Incorporated (US) 2009-08-19 EP disclosed
WO-2008085575-A2 POLYPEPTIDES AND BIOSYNTHETIC PATHWAYS FOR THE PRODUCTION OF STEREOISOMERS OF MONATIN AND THEIR PRECURSORS CARGILL, INCORPORATED (US) 2008-07-17 WO disclosed