SCHEMBL4478348

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4477211	0.89	CNR2 (0.58)	CNR2P2RX7TACR1MGLLTACR2
	SCHEMBL4468625	0.89	CNR2 (0.52)	CNR2P2RX7MAPT
	SCHEMBL4487562	0.89	CNR2 (0.55)	CNR2P2RX7TACR1MGLLGRM2
	SCHEMBL13708808	0.87	CNR2 (0.53)	CNR2P2RX7TACR1MGLLTACR2
	SCHEMBL4488066	0.86	CNR2 (0.57)	CNR2TACR1TACR2DRD2DRD4
	SCHEMBL4475198	0.86	CNR2 (0.53)	CNR2P2RX7TACR1MGLLTACR2
	SCHEMBL4467170	0.85	CNR2 (0.54)	CNR2P2RX7TACR1MGLLTACR2
	SCHEMBL4472711	0.85	ROCK1 (0.50)	CNR2MGLLDRD2DRD4GRM2
	SCHEMBL4472709	0.85	ROCK1 (0.50)	CNR2MGLLDRD2DRD4GRM2
	SCHEMBL4487561	0.85	ROCK1 (0.50)	CNR2MGLLDRD2DRD4GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.