Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.53 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.53 |
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 0.53 |
| ▸ | MECP2 | P51608 | 1/20 | 0.53 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | CCR1 | P32246 | 3/20 | 0.47 |
| ▸ | CCR5 | P51681 | 3/20 | 0.47 |
| ▸ | CCR8 | P51685 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4475785 | 0.86 | MAP4K4 (0.55) | KDM4ETDP1KCNN1KCNN2KCNN3 | |
| SCHEMBL4476417 | 0.81 | KMT2A (0.54) | SLC2A1KDM4ETDP1KMT2ACYP1A2 | |
| SCHEMBL7152644 | 0.80 | KDM4E (0.77) | SLC2A1KDM4ETDP1ALOX15L3MBTL1 | |
| SCHEMBL5022535 | 0.78 | KMT2A (0.55) | SLC2A1KDM4ETDP1KCNN1KCNN2 | |
| Hydrochloric Acid SCHEMBL4902758 | 0.77 | SMN1; SMN2 (0.61) | KDM4ETDP1KCNN1KCNN2KCNN3 | |
| SCHEMBL221242 | 0.75 | KMT2A (0.76) | KDM4ETDP1KCNN1KCNN2KCNN3 | |
| SCHEMBL29391624 | 0.75 | KMT2A (0.76) | KDM4ETDP1KCNN1KCNN2KCNN3 | |
| SCHEMBL20919346 | 0.74 | KMT2A (0.57) | KDM4ETDP1KCNN1KCNN2KCNN3 | |
| SCHEMBL20919383 | 0.74 | KDM4E (0.68) | KDM4ETDP1KCNN1KCNN2KCNN3 | |
| SCHEMBL13133534 | 0.73 | KDM4E (0.70) | SLC2A1KDM4ETDP1ALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560464-B2 | Polycyclic pyrimidines as potassium ion channel modulators | ICAGEN, INC. (US) | 2009-07-14 | — | — | US | disclosed |
| US-20050267089-A1 | Polycyclic pyrimidines as potassium ion channel modulators | ICAGEN, INC. (US) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267089-A1 | Polycyclic pyrimidines as potassium ion channel modulators | KCNJ2, KCNJ1, KCNJ11 | SLC2A1 1482/4885KDM4E 1336/4885TDP1 1750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.