Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 16/20 | 0.80 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.80 |
| ▸ | ADRB2 | P07550 | 12/20 | 0.75 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.72 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.71 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4472487 | 0.99 | ADRB3 (0.78) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL7149376 | 0.90 | ADRB3 (0.81) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL7207154 | 0.90 | ADRB3 (0.81) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL7149375 | 0.90 | ADRB3 (0.81) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL9468416 | 0.89 | ADRB3 (1.00) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL9468401 | 0.88 | SLC2A1 (0.81) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL11273021 | 0.87 | ADRB3 (0.77) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL7148235 | 0.86 | ADRB3 (0.96) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL7148233 | 0.86 | ADRB3 (0.96) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL10433618 | 0.86 | SLC2A1 (0.78) | ADRB3ADRB1ADRB2ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629366-B2 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20060100252-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-11 | — | — | US | disclosed |
| US-7037938-B2 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20040006143-A1 | For therapy of urinary incontinence | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100252-A1 | Aminoalcohol derivatives | H1-0, CHRM2, CHRM1 | ADRB3 130/4885ADRB1 39/4885ADRB2 40/4885 |
| US-20040006143-A1 | For therapy of urinary incontinence | H1-0, HRH2, H1-2 | ADRB3 568/4885ADRB1 256/4885ADRB2 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.