⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23113893 | 0.78 | — | — | |
| SCHEMBL1832217 | 0.78 | — | — | |
| SCHEMBL8458175 | 0.73 | — | — | |
| SCHEMBL23266336 | 0.73 | CES1 (0.37) | — | |
| SCHEMBL14152761 | 0.72 | CES1 (0.36) | — | |
| SCHEMBL19065228 | 0.68 | — | — | |
| SCHEMBL19691092 | 0.68 | SMYD3 (0.43) | — | |
| SCHEMBL15515155 | 0.66 | TP53 (0.46) | — | |
| SCHEMBL24922320 | 0.64 | — | — | |
| SCHEMBL108190 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951946-B2 | Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates | LEXICON PHARMACEUTICALS, INC. (US) | 2005-10-04 | — | — | US | claimed |
| US-20040019215-A1 | Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates | LEXICON PHARMACEUTICALS, INC. | 2004-01-29 | — | — | US | claimed |
| EP-0805816-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-11-12 | — | — | EP | claimed |
| US-20260138991-A1 | SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES | MOMA THERAPEUTICS INC (US) | 2026-05-21 | — | — | US | disclosed |
| EP-4705298-A2 | SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES | Moma Therapeutics, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| US-12559508-B2 | Semi-saturated bicyclic derivatives and related uses | MOMA THERAPEUTICS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-20250230171-A1 | SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES | MOMA THERAPEUTICS, INC. | 2025-07-17 | — | — | US | disclosed |
| CN-115340536-B | Amide compound containing 1,2, 4-oxadiazole and salt, preparation method and application thereof | 华东理工大学 | 2024-12-10 | — | — | CN | disclosed |
| US-20240368114-A1 | INDAZOLES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX INC (US) | 2024-11-07 | — | — | US | disclosed |
| WO-2024211836-A2 | SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES | MOMA THERAPEUTICS, INC. (US) | 2024-10-10 | — | — | WO | disclosed |
| EP-3833672-B1 | TRICYCLIC INHIBITORS OF HEPATITIS B VIRUS | OSPEDALE SAN RAFFAELE SRL (IT) | 2024-09-18 | — | — | EP | disclosed |
| EP-1487828-B1 | MORPHOLINYL-UREA DERIVATIVES FOR USE OF THE TREATMENT OF INFLAMATORY DISEASES | GLAXO GROUP LTD (GB) | 2008-11-05 | — | — | EP | disclosed |
| US-20060063765-A1 | Novel compounds | GLAXO GROUP LIMITED (GB) | 2006-03-23 | — | — | US | disclosed |
| US-6951946-B2 | Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates | LEXICON PHARMACEUTICALS, INC. (US) | 2005-10-04 | — | — | US | disclosed |
| US-20050154211-A1 | Large scale synthesis of 1,2,4- and 1,3,4- oxadiazole carboxylates | KOLB HARTMUTH C (US) | 2005-07-14 | — | — | US | disclosed |
| US-20040019215-A1 | Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates | LEXICON PHARMACEUTICALS, INC. | 2004-01-29 | — | — | US | disclosed |
| EP-0647635-B1 | Herbicidal 1,2,4-oxadiazolecarboxylic acids amides, esters or halides | SHELL INT RESEARCH (NL) | 1998-07-08 | — | — | EP | disclosed |
| EP-0647635-A1 | Herbicidal 1,2,4-oxadiazolecarboxylic acids amides, esters or halides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1995-04-12 | — | — | EP | disclosed |
| US-4159336-A | ANTIALLERGENS | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4069332-A | 5,5'-PHENYLENEBIS(1,2,4-OXADIAZOLE-3-CARBOXYLIC ACIDS OR ESTERS) | THE UPJOHN COMPANY (US) | 1978-01-17 | — | — | US | disclosed |