Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3837280 | 0.91 | MCHR1 (0.68) | MCHR1KDRSCN10ALMNATP53 | |
| SCHEMBL3835961 | 0.89 | MCHR1 (0.60) | MCHR1LMNATP53MAPTTHRB | |
| SCHEMBL3831980 | 0.87 | MCHR1 (0.67) | MCHR1SCN10AHDAC4 | |
| SCHEMBL3832012 | 0.86 | MCHR1 (0.56) | MCHR1MAPTNR2E3HDAC6KMT2A | |
| SCHEMBL13817998 | 0.85 | MCHR1 (0.60) | MCHR1KDRMAPTPOLB | |
| SCHEMBL3837969 | 0.76 | MCHR1 (0.68) | MCHR1KDRLMNAMAPTHDAC4 | |
| SCHEMBL13817977 | 0.76 | MCHR1 (0.74) | MCHR1KDRLMNAMAPTPOLB | |
| SCHEMBL3831523 | 0.76 | MCHR1 (0.82) | MCHR1KDRMAPTPOLBATM | |
| SCHEMBL3833412 | 0.75 | MCHR1 (0.65) | MCHR1 | |
| SCHEMBL3831493 | 0.75 | MCHR1 (0.65) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541477-B2 | Antagonists to melanin-concentrating hormone receptor comprising benzimidazole derivative as active ingredient | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-06-02 | — | — | US | disclosed |
| US-7541477-B2 | Antagonists to melanin-concentrating hormone receptor comprising benzimidazole derivative as active ingredient | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-06-02 | — | — | US | disclosed |
| US-7541477-B2 | Antagonists to melanin-concentrating hormone receptor comprising benzimidazole derivative as active ingredient | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-06-02 | — | — | US | disclosed |
| EP-1553089-A1 | ANTAGONIST OF MELANIN-CONCENTRATING HORMONE RECEPTOR COMPRISING BENZIMIDAZOLE DERIVATIVE AS ACTIVE INGREDIENT | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-07-13 | — | — | EP | disclosed |