Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3042690 | 1.00 | MEN1 (0.56) | MEN1KMT2AATMABCB1MAPT | |
| SCHEMBL3042761 | 1.00 | MEN1 (0.56) | MEN1KMT2AATMABCB1MAPT | |
| Hydrochloric Acid SCHEMBL3144341 | 0.99 | MEN1 (0.58) | MEN1KMT2AATMABCB1MAPT | |
| SCHEMBL3041578 | 0.95 | ABCB1 (0.54) | MEN1KMT2AATMABCB1MAPT | |
| SCHEMBL29375850 | 0.95 | ABCB1 (0.54) | MEN1KMT2AATMABCB1MAPT | |
| SCHEMBL13515655 | 0.88 | ABCB1 (0.57) | MEN1KMT2AATMABCB1MAPT | |
| SCHEMBL3255019 | 0.88 | ABCB1 (0.57) | MEN1KMT2AATMABCB1MAPT | |
| SCHEMBL3045796 | 0.87 | MEN1 (0.58) | MEN1KMT2AATMABCB1MAPT | |
| SCHEMBL13515707 | 0.87 | MEN1 (0.58) | MEN1KMT2AATMABCB1MAPT | |
| SCHEMBL3038397 | 0.86 | MAPT (0.57) | MEN1KMT2AATMABCB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054033-A2 | LIQUID PREPARATION | Asubio Pharma Co., Ltd. (JP) | 2009-05-06 | — | — | EP | claimed |
| WO-2008016165-A2 | LIQUID PREPARATION | ASUBIO PHARMA CO., LTD. (JP) | 2008-02-07 | — | — | WO | claimed |
| US-7642262-B2 | Arylipiperdinopropanol and arylipiperazinopropanol derivatives and pharmaceuticals containing the same | ASUBIO PHARMA CO., LTD. (JP) | 2010-01-05 | — | — | US | disclosed |