⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12471092 | 0.67 | — | — | |
| SCHEMBL790735 | 0.65 | — | — | |
| SCHEMBL450323 | 0.65 | — | — | |
| SCHEMBL6292701 | 0.65 | — | — | |
| SCHEMBL533401 | 0.64 | — | — | |
| SCHEMBL6292671 | 0.64 | — | — | |
| SCHEMBL56855 | 0.64 | — | — | |
| SCHEMBL7325844 | 0.64 | — | — | |
| SCHEMBL2905432 | 0.63 | — | — | |
| SCHEMBL29291322 | 0.59 | GRM5 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 476 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149231-A1 | PARP7 INHIBITORS AND USES THEREOF | Angel Pharmaceutical Co., Ltd. (CN) | 2024-07-18 | — | — | WO | claimed |
| WO-2024149234-A1 | PARP7 INHIBITORS AND USES THEREOF | Angel Pharmaceutical Co., Ltd. (CN) | 2024-07-18 | — | — | WO | claimed |
| CN-114621209-B | 1,2, 3-Thiadiazole acetonitrile derivatives, and preparation method and application thereof | 南开大学 | 2024-06-14 | — | — | CN | claimed |
| EP-4370110-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | Denali Therapeutics Inc. (US) | 2024-05-22 | — | — | EP | claimed |
| CN-117940120-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2024-04-26 | — | — | CN | claimed |
| US-20240034737-A1 | Heterocyclic Derivatives as P2X7 Receptor Antagonists | BREYE THERAPEUTICS APS (DK) | 2024-02-01 | — | — | US | claimed |
| US-20240034728-A1 | PYRIDAZINONES AS PARP7 INHIBITORS | RIBON THERAPEUTICS, INC. | 2024-02-01 | — | — | US | claimed |
| US-20230416205-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | TENVIE THERAPEUTICS, INC. | 2023-12-28 | — | — | US | claimed |
| CN-114656462-B | N-containing heterocyclic aromatic hydrazone derivatives, and preparation method and application thereof | 南开大学 | 2023-12-19 | — | — | CN | claimed |
| CN-117157291-A | Heterocyclic derivatives as P2X7 receptor antagonists | 布雷耶疗法有限公司 | 2023-12-01 | — | — | CN | claimed |
| CN-1419450-A | Nitrate salts of antimicrobial drugs | NICOX SA (FR) | 2003-05-21 | — | — | CN | claimed |
| EP-1253924-A1 | NITRATE SALTS OF ANTIMICROBIAL AGENTS | NICOX S.A. (FR) | 2002-11-06 | — | — | EP | claimed |
| WO-2001054691-A1 | NITRATE SALTS OF ANTIMICROBIAL AGENTS | NICOX, S.A. (FR) | 2001-08-02 | — | — | WO | claimed |
| US-5977110-A | Substituted cyclohexylamines as central nervous systems agents | WARNER-LAMBERT COMPANY (US) | 1999-11-02 | — | — | US | claimed |
| WO-1997011070-A1 | SUBSTITUTED CYCLOHEXYLAMINES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER-LAMBERT COMPANY (US) | 1997-03-27 | — | — | WO | claimed |
| EP-0096004-B1 | SULFONYL(THIO)UREAS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR GROWTH REGULATING AGENTS | CIBA-GEIGY AG (CH) | 1989-04-26 | — | — | EP | claimed |
| EP-0096004-A2 | Sulfonyl(thio)ureas, process for their preparation and their use as herbicides and/or growth regulating agents | CIBA-GEIGY AG (CH) | 1983-12-07 | — | — | EP | claimed |
| US-4333936-A | Novel amidino-benzylpyrimidines, processes for their manufacture and antibacterial and antiprotozoal use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | claimed |
| EP-0000336-B1 | N-BENZYLPYRIMIDINYL-AMIDINES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1981-04-15 | — | — | EP | claimed |
| EP-0000336-A1 | N-benzylpyrimidinyl-amidines, process for their preparation and medicines containing them | BASF Aktiengesellschaft (DE) | 1979-01-24 | — | — | EP | claimed |