SCHEMBL4482440

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13141321	0.85	MAPT (0.54)	CA1CA2MAPTCA12CA7
	SCHEMBL1936827	0.83	MAPT (0.47)	CA1CA2MAPTCA12CA7
	SCHEMBL1934376	0.82	MAPT (0.46)	CA1CA2MAPTCA12CA7
	SCHEMBL6620223	0.82	MAPT (0.46)	CA1CA2MAPTCA12CA7
	SCHEMBL1934170	0.81	MAPT (0.54)	CA1CA2MAPTCA12CA7
	SCHEMBL9131564	0.80	MAPT (0.47)	CA1CA2MAPTCA12CA7
	SCHEMBL6624152	0.80	MAPT (0.45)	CA1CA2MAPTCA12CA7
	SCHEMBL1936208	0.80	MAPT (0.53)	CA1CA2MAPTCA12CA7
	SCHEMBL6087188	0.79	CYP1A2 (0.53)	CA1CA2MAPTCA12CA7
	SCHEMBL382018	0.79	CA12 (0.53)	CA1CA2MAPTCA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.