SCHEMBL44832

SCHEMBL44832

N[C@@H](Cc1ccc(Br)cc1)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.69
PTGS1 P23219 3/20 0.68
ALPI P09923 1/20 0.68
PKM P14618 1/20 0.68
XIAP P98170 1/20 0.68
PTPRC P08575 1/20 0.58
HIF1A Q16665 4/20 0.58
ALOX15 P16050 3/20 0.58
KDM4E B2RXH2 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
HSD17B10 Q99714 2/20 0.58
USP2 O75604 1/20 0.58
EGFR P00533 1/20 0.58
LCK P06239 1/20 0.58
FYN P06241 1/20 0.58
ADORA3 P0DMS8 1/20 0.58
HTR2A P28223 1/20 0.58
PTGS2 P35354 1/20 0.58
RECQL P46063 1/20 0.58
TPH1 P17752 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44831 1.00 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL244718 1.00 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL975336 0.98 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL27515070 0.98 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL5878327 0.98 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL31370558 0.94 SLC7A5 (0.62) SLC7A5PTGS1ALPIPKMXIAP
Alanine SCHEMBL18770349 0.93 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
Alanine SCHEMBL18770348 0.93 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL2310526 0.89 SLC7A5 (0.83) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL8121390 0.84 EPHX1 (0.50) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6188 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630588-B2 Bicyclic peptide ligands specific for CD137 BICYCLETX LIMITED (GB) 2026-05-19 US claimed
US-12590137-B2 Meditope-enabled T cells CITY OF HOPE (US) 2026-03-31 US claimed
US-12577575-B2 Methods and compositions for promoting non-natural amino acid-containing protein production AMBRX, INC. (US) 2026-03-17 US claimed
EP-4225772-B1 CYCLIC APELIN RECEPTOR AGONISTS NXERA PHARMA UK LTD (GB) 2026-02-25 EP claimed
US-12552837-B2 Bicyclic peptide ligands with detectable moieties and uses thereof Bicyclerd Limited (GB) 2026-02-17 US claimed
EP-4689127-A1 RF1 KO E. COLI STRAINS Sutro Biopharma, Inc. (US) 2026-02-11 EP claimed
US-12540197-B2 Anti-tissue factor antibodies and antibody conjugates, compositions comprising anti-tissue factor antibodies or antibody conjugates, and methods of making and using anti-tissue factor antibodies and antibody conjugates SUTRO BIOPHARMA, INC. (US) 2026-02-03 US claimed
EP-3727462-B1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BICYCLERD LTD (GB) 2025-11-05 EP claimed
EP-4644570-A1 HELICASE MUTANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN HIGH-THROUGHPUT SEQUENCING BGI Shenzhen (CN) 2025-11-05 EP claimed
US-20250325632-A1 CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES Synthorx, Inc. (US) 2025-10-23 US claimed
EP-1003771-A1 LINEAR PEPTIDES DERIVED FROM ANTIBIOTIC PEPTIDES, PREPARATION AND USE FOR VECTORING ACTIVE SUBSTANCES Synt:em (S.A.) (FR) 2000-05-31 EP claimed
EP-0920307-A2 DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM Roche Diagnostics GmbH (DE) 1999-06-09 EP claimed
WO-1999007728-A2 LINEAR PEPTIDES DERIVED FROM ANTIBIOTIC PEPTIDES, PREPARATION AND USE FOR VECTORING ACTIVE SUBSTANCES SYNT:EM (S.A.) (FR) 1999-02-18 WO claimed
WO-1998037097-A1 MSH-RECEPTOR SUBTYPE SELECTIVE CYCLIC PEPTIDES WAPHARM AB (SE) 1998-08-27 WO claimed
WO-1998006386-A2 DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM ROCHE DIAGNOSTICS GMBH (DE) 1998-02-19 WO claimed
US-5470830-A Motilin-like polypeptides that inhibit gastrointestinal motor activity OHMEDA PHARMACEUTICAL PRODUCTS DIVISION INC. (US) 1995-11-28 US claimed
US-5422341-A Antidiabetic agents OHMEDA PHARMACEUTICAL PRODUCTS DIVISION INC. (US) 1995-06-06 US claimed
EP-0647656-A1 Motilin-like polypeptides that inhibit gastrointestinal motor activity Ohmeda Pharmaceutical Products Division Inc. (US) 1995-04-12 EP claimed
EP-0646601-A1 Motilin-like polypeptides with gastrointestinal motor stimulating activity Ohmeda Pharmaceutical Products Division Inc. (US) 1995-04-05 EP claimed
US-4407952-A OF GENETICALLY ENGINEERED ESCHERICHIA AJINOMOTO COMPANY INCORPORATED (JP) 1983-10-04 US claimed