Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Ethyl Ester SCHEMBL2431230 | 0.95 | TSHR (0.46) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL5654267 | 0.90 | TSHR (0.42) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL423013 | 0.85 | TSHR (0.54) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL8637472 | 0.84 | TSHR (0.46) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL2379322 | 0.83 | TSHR (0.52) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL10729431 | 0.83 | TSHR (0.41) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL27639683 | 0.81 | TSHR (0.50) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL2703768 | 0.81 | TSHR (0.54) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL7521917 | 0.81 | TSHR (0.54) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL11847163 | 0.81 | TSHR (0.43) | TSHRHPGDHCAR2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572463-B2 | Oral dosage forms | GRUENENTHAL GMBH (DE) | 2009-08-11 | — | — | US | disclosed |