SCHEMBL4483901

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6077668	0.88	HDAC1 (0.57)	HDAC1HDAC3HDAC2NCOR2HDAC4
	SCHEMBL6383504	0.85	KDM4E (0.42)	HDAC1HDAC3HDAC2NCOR2MAPK1
	SCHEMBL3542006	0.82	EPHX2 (0.51)	HDAC1HDAC3HDAC2MAPK1HDAC4
	SCHEMBL4490584	0.80	HDAC3 (0.59)	HDAC1HDAC3HDAC2NCOR2MAPK1
	SCHEMBL13162252	0.79	KDM4E (0.52)	MAPK1
	SCHEMBL14500184	0.77	NPC1 (0.50)	HDAC1HDAC6
	SCHEMBL12684742	0.77	HDAC1 (0.76)	HDAC1HDAC3HDAC2NCOR2MAPK1
	SCHEMBL8401704	0.77	HDAC1 (0.89)	HDAC1HDAC3HDAC2NCOR2MAPK1
	SCHEMBL5223727	0.76	PTGS1 (0.72)	HDAC1HDAC3HDAC2NCOR2MAPK1
	SCHEMBL3543155	0.75	CYP2D6 (0.52)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.