Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4478294 | 0.88 | MAPK14 (0.54) | MAPK14 | |
| SCHEMBL4381149 | 0.79 | MAPK14 (0.55) | MAPK14 | |
| SCHEMBL4380696 | 0.76 | MAPK14 (0.56) | MAPK14 | |
| SCHEMBL4382794 | 0.74 | MAPK14 (0.56) | MAPK14 | |
| SCHEMBL6500546 | 0.71 | MAPK14 (0.49) | MAPK14 | |
| SCHEMBL29593468 | 0.71 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL4376488 | 0.71 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL29594345 | 0.69 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL4384361 | 0.69 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL4382507 | 0.68 | MCHR1 (0.55) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629363-B2 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |