Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 10/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.43 |
| ▸ | OXTR | P30559 | 9/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.43 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2497563 | 0.81 | AVPR1A (0.43) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL2495296 | 0.80 | AVPR1B (0.60) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL2495745 | 0.80 | AVPR1A (0.42) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL4484568 | 0.80 | AVPR1B (0.63) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL2499389 | 0.79 | AVPR1A (0.52) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL4479387 | 0.79 | AVPR1A (0.52) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL2499338 | 0.79 | AVPR1A (0.52) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL2500497 | 0.79 | AVPR1A (0.52) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL2495932 | 0.76 | AVPR1B (0.57) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL2499794 | 0.75 | AVPR1B (0.58) | AVPR1BAVPR1AOXTRAVPR2GPR65 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528124-B2 | 1,3-dihydro-2H-indol-2-one derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-05-05 | — | — | US | disclosed |
| US-20060276449-A1 | 1,3-Dihydro-2h-indol-2-one derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1659121-A1 | 1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276449-A1 | 1,3-Dihydro-2h-indol-2-one derivative | AVPR1B, AVPR2, AVPR1A | AVPR1B 1/4885AVPR1A 3/4885OXTR 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.