Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 14/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4485290 | 1.00 | KCNH2 (1.00) | KCNH2GAAALDH1A1TSHRHSD17B10 | |
| SCHEMBL4485277 | 1.00 | KCNH2 (1.00) | KCNH2GAAALDH1A1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL4485249 | 0.99 | KCNH2 (0.98) | KCNH2GAA | |
| Hydrochloric Acid SCHEMBL4485248 | 0.99 | KCNH2 (0.98) | KCNH2GAA | |
| Hydrochloric Acid SCHEMBL4485251 | 0.99 | KCNH2 (0.98) | KCNH2GAA | |
| SCHEMBL4496596 | 0.90 | KCNH2 (0.82) | KCNH2 | |
| SCHEMBL4496588 | 0.90 | KCNH2 (0.82) | KCNH2 | |
| SCHEMBL4496583 | 0.90 | KCNH2 (0.82) | KCNH2 | |
| SCHEMBL13633348 | 0.90 | KCNH2 (0.81) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4483213 | 0.90 | KCNH2 (0.81) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622481-B2 | Antibacterial compounds | GLAXO GROUP LIMITED (GB) | 2009-11-24 | — | — | US | claimed |