⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746830 | 0.69 | CYP1A1 (0.36) | — | |
| SCHEMBL449784 | 0.67 | — | — | |
| SCHEMBL2177631 | 0.65 | — | — | |
| SCHEMBL2176878 | 0.64 | — | — | |
| SCHEMBL17007321 | 0.64 | — | — | |
| SCHEMBL2179003 | 0.64 | — | — | |
| SCHEMBL15689573 | 0.64 | — | — | |
| SCHEMBL303339 | 0.62 | — | — | |
| SCHEMBL9079389 | 0.62 | — | — | |
| SCHEMBL4918727 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373825-A1 | NITRILE SUMO INHIBITORS AND USES THEREOF | Suvalent Therapeutics, Inc. (US) | 2024-05-29 | — | — | EP | claimed |
| WO-2023004376-A1 | NITRILE SUMO INHIBITORS AND USES THEREOF | Suvalent Therapeutics, Inc. (US) | 2023-01-26 | — | — | WO | claimed |
| EP-2375898-B1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-16 | — | — | EP | claimed |
| US-8980888-B2 | Pyrazole derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-03-17 | — | — | US | claimed |
| US-20140378447-A1 | NOVEL PYRAZOLE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2014-12-25 | — | — | US | claimed |
| US-20140128373-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. | 2014-05-08 | — | — | US | claimed |
| CN-103517710-A | Compounds and methods for kinase modulation, and indications therefor | PLEXXIKON INC | 2014-01-15 | — | — | CN | claimed |
| EP-2672967-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | Plexxikon, Inc. (US) | 2013-12-18 | — | — | EP | claimed |
| WO-2012109075-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2012-08-16 | — | — | WO | claimed |
| EP-4373825-A1 | NITRILE SUMO INHIBITORS AND USES THEREOF | Suvalent Therapeutics, Inc. (US) | 2024-05-29 | — | — | EP | disclosed |
| WO-2024086194-A1 | COMBINATION THERAPY FOR TREATMENT OF CANCER | Suvalent Therapeutics, Inc. (US) | 2024-04-25 | — | — | WO | disclosed |
| US-20230277534-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. | 2023-09-07 | — | — | US | disclosed |
| US-20230159561-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC CORP (US) | 2023-05-25 | — | — | US | disclosed |
| US-11641858-B2 | Agricultural chemicals | REDAG CROP PROTECTION LTD. (GB) | 2023-05-09 | — | — | US | disclosed |
| US-5633256-A | Certain pyrimidinyloxy-phenyl acrylates, derivatives thereof and their fungicidal use | ZENECA LIMITED (GB) | 1997-05-27 | — | — | US | disclosed |
| US-5602076-A | INSECTICIDES, NEMATOCIDES | ZENECA LIMITED (GB) | 1997-02-11 | — | — | US | disclosed |
| US-5470819-A | Plant growth regulators, insecticides | ZENECA LIMITED (GB) | 1995-11-28 | — | — | US | disclosed |
| US-5438059-A | Derivatives of propenoic acid; stereoisomers; applying to plants | ZENECA LIMITED (GB) | 1995-08-01 | — | — | US | disclosed |
| US-5057146-A | CERTAIN 2-PYRIDYL OXY-PHENYL ACRYLATES HAVING FUNGICIDAL, INSECTICIDAL, NEMATOCIDAL AND PLANT GROWTH REGULATING ACTIVITY | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-15 | — | — | US | disclosed |
| US-5021581-A | Fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-04 | — | — | US | disclosed |