SCHEMBL4488154

SCHEMBL4488154

S[N]S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14562972 0.67
SCHEMBL11844833 0.61
SCHEMBL411877 0.61
SCHEMBL2938390 0.58
SCHEMBL23453889 0.50
SCHEMBL1316766 0.50
SCHEMBL25218393 0.50
SCHEMBL10415641 0.50
SCHEMBL6282335 0.50
SCHEMBL29491022 0.50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117396074-A Fungicidal compositions containing oxadiazole compounds PI工业有限公司 2024-01-12 CN claimed
US-11229624-B2 FABP4 as a therapeutic target in skin diseases TICURE LTD. (IL) 2022-01-25 US disclosed
US-20200138779-A1 FABP4 AS A THERAPEUTIC TARGET IN SKIN DISEASES TICURE LTD. (IL) 2020-05-07 US disclosed
EP-3532049-A1 FABP4 AS A THERAPEUTIC TARGET IN SKIN DISEASES Ticure Ltd. (IL) 2019-09-04 EP disclosed
WO-2018078624-A1 FABP4 AS A THERAPEUTIC TARGET IN SKIN DISEASES TICURE LTD. (IL) 2018-05-03 WO disclosed
US-9302982-B2 Pharmaceutical dopamine glycoconjugate compositions and methods of their preparation and use GLYCON LLC (US) 2016-04-05 US disclosed
US-20130203855-A1 Pharmaceutical Dopamine Glycoconjugate Compositions and Methods of Their Preparation and Use GLYCON LLC (US) 2013-08-08 US disclosed
US-8252752-B2 An amidation product of ribosyl or glucosyl saccharide and a dopamine or derivative (forms amide through amine and carboxylic group); useful for treating neurological diseases including Parkinson's GLYCON LLC (US) 2012-08-28 US disclosed
US-7629472-B2 Method for producing optically active compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-12-08 US disclosed
US-20080194802-A1 PHARMACEUTICAL DOPAMINE GLYCOCONJUGATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE GLYCON LLC 2008-08-14 US disclosed
US-7247732-B2 Method for producing optically active compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-07-24 US disclosed
US-20060229457-A1 Method for producing optically active compound YAMANO TORU 2006-10-12 US disclosed
EP-1385857-A4 PHARMACEUTICAL DOPAMINE GLYCOCONJUGATE COMPOSITIONS AND METHODS OF THEIR PREPARATION INTERNAT MEDICAL INNOVATIONS I (US) 2006-09-06 EP disclosed
US-7084278-B2 Process for production of optically active compounds TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-08-01 US disclosed
US-20050250739-A1 Pharmaceutical dopamine glycoconjugate compositions and methods of their preparation and use GLYCON LLC 2005-11-10 US disclosed
US-20050107433-A1 Process for production of optically active compounds TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-05-19 US disclosed
EP-1489070-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE COMPOUNDS Takeda Chemical Industries, Ltd. (JP) 2004-12-22 EP disclosed
EP-1385857-A1 PHARMACEUTICAL DOPAMINE GLYCOCONJUGATE COMPOSITIONS AND METHODS OF THEIR PREPARATION International Medical Innovations, Inc. (US) 2004-02-04 EP disclosed
US-6548484-B1 An amidation product of ribosyl or glucosyl saccharide and a dopamine or derivative ( forms a amide through amine and carboxylic group); useful for treating neurological diseases including Parkinson's and related diseases INTERNATIONAL MEDICAL INNOVATIONS, INC. 2003-04-15 US disclosed
WO-2001079244-A1 PHARMACEUTICAL DOPAMINE GLYCOCONJUGATE COMPOSITIONS AND METHODS OF THEIR PREPARATION INTERNATIONAL MEDICAL INNOVATIONS, INC. (US) 2001-10-25 WO disclosed