⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4504385 | 1.00 | — | — | |
| SCHEMBL4489882 | 1.00 | — | — | |
| SCHEMBL5727853 | 1.00 | — | — | |
| SCHEMBL13686565 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27664351 | 0.97 | CYP2C9 (0.38) | — | |
| SCHEMBL8300772 | 0.83 | CYP2C9 (0.46) | — | |
| SCHEMBL24269492 | 0.82 | — | — | |
| SCHEMBL20811096 | 0.82 | — | — | |
| SCHEMBL25101528 | 0.82 | — | — | |
| SCHEMBL10273860 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108713020-A | The method for preparing antibody-rifamycin conjugate | 豪夫迈·罗氏有限公司 | 2018-10-26 | — | — | CN | claimed |
| CN-108456183-A | The preparation method and intermediate of Gedatolisib | 上海工程技术大学 | 2018-08-28 | — | — | CN | claimed |
| CN-102781922-A | TGR5 agonists | EXELIXIS INC | 2012-11-14 | — | — | CN | claimed |
| CN-102056927-A | Fused nitrogen containing heterocycles and compositions thereof as kinase inhibitors | IRM LLC | 2011-05-11 | — | — | CN | claimed |
| US-20230210834-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2023-07-06 | — | — | US | disclosed |
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |
| CN-110526915-A | A kind of preparation method of anaplastic lymphoma kinase inhibitor | SHOUYAO HOLDINGS BEIJING CO LTD | 2019-12-03 | — | — | CN | disclosed |
| CN-110526941-A | A kind of azolopyrimidines containing m-chloroaniline class substituent group, preparation method and applications | BEIJING SAITE MINGQIANG MEDICINE TECH CO LTD | 2019-12-03 | — | — | CN | disclosed |
| CN-110467638-A | A kind of double amino Chloropyrimide class compounds containing m-chloroaniline class substituent group, preparation method and applications | BEIJING SAITE MINGQIANG MEDICINE TECH CO LTD | 2019-11-19 | — | — | CN | disclosed |
| CN-110467615-A | Azolopyrimidines include its pharmaceutical composition and its preparation method and application | SICHUAN KELUN BOTAI BIOMEDICAL CO LTD | 2019-11-19 | — | — | CN | disclosed |
| CN-110467637-A | A kind of double amino Chloropyrimide class compounds containing phosphinoxides substituted aniline, preparation method and applications | BEIJING SAITE MINGQIANG MEDICINE TECH CO LTD | 2019-11-19 | — | — | CN | disclosed |
| CN-110317191-A | A kind of pyridine-heterocyclic compound and its application as CXCR4 inhibitor | 苏州云轩医药科技有限公司 | 2019-10-11 | — | — | CN | disclosed |
| US-6235747-B1 | NITRIC OXIDE SYNTHASE INHIBITOR | PFIZER INC. | 2001-05-22 | — | — | US | disclosed |
| EP-1042748-A1 | MAGNETIC RECORDING MEDIUM BASED ON A POLYURETHANE PREPOLYMER CONTAINING HYDROXYL AND AMINO GROUPS | EMTEC Magnetics GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-2000028531-A1 | UV-RADIATION-HARDENABLE BINDER COMPOSITION FOR MAGNETIC RECORDING MEDIA AND PHOTOINITIATOR MIXTURE | EMTEC MAGNETICS GMBH (DE) | 2000-05-18 | — | — | WO | disclosed |
| WO-1999034357-A1 | MAGNETIC RECORDING MEDIUM BASED ON A POLYURETHANE PREPOLYMER CONTAINING HYDROXYL AND AMINO GROUPS | EMTEC MAGNETICS GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |
| CN-1215391-A | 6-phenylpyridyl-2-amine derivatives | PFIZER (US) | 1999-04-28 | — | — | CN | disclosed |
| EP-0891332-A1 | 6-PHENYLPYRIDYL-2-AMINE DERIVATIVES | PFIZER INC. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036871-A1 | 6-PHENYLPYRIDYL-2-AMINE DERIVATIVES | PFIZER INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| US-4118368-A | DERIVATIVES OF 2,6-DIMETHYL-2,6-DIALKYL-4-AMINO-4-CARBOXYLATE-PIPERIDINES | SANKYO COMPANY LIMITED (JP) | 1978-10-03 | — | — | US | disclosed |