Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.73 |
| ▸ | MAPT | P10636 | 11/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.73 |
| ▸ | NPC1 | O15118 | 6/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.73 |
| ▸ | RAB9A | P51151 | 5/20 | 0.73 |
| ▸ | THRB | P10828 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 4/20 | 0.51 |
| ▸ | CRHBP | P24387 | 2/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.51 |
| ▸ | IDE | P14735 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4490166 | 1.00 | MEN1 (0.73) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL13709032 | 0.83 | MEN1 (0.69) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL4505264 | 0.82 | HPGD (0.58) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL4505267 | 0.82 | MEN1 (0.52) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL4505272 | 0.82 | HPGD (0.58) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL13026070 | 0.82 | KMT2A (0.87) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL10036033 | 0.80 | MEN1 (0.87) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL10036009 | 0.80 | MEN1 (0.76) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL11688300 | 0.80 | MEN1 (0.76) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL11688292 | 0.80 | MEN1 (0.76) | MEN1KMT2AMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592188-B2 | environmentally sensitive fluorescent dye covalently linked to a binding domain which has specific affinity for a target molecule; fluorescence resonance energy transfer; detecting changes in the binding, conformational change; detecting human immunodeficiency virus | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-09-22 | — | — | US | disclosed |