Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.64 |
| ▸ | LCK | P06239 | 3/20 | 0.51 |
| ▸ | KDR | P35968 | 3/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.51 |
| ▸ | DDR2 | Q16832 | 4/20 | 0.48 |
| ▸ | KIT | P10721 | 3/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3526126 | 0.84 | MAPK14 (0.84) | MAPK14LCKKDRCSF1RDDR2 | |
| SCHEMBL4501762 | 0.84 | MAPK14 (0.57) | MAPK14LCKKDRCSF1R | |
| SCHEMBL4493100 | 0.83 | MAPK14 (0.53) | MAPK14LCKKDRCSF1RRIPK2 | |
| SCHEMBL4503641 | 0.82 | MAPK14 (0.53) | MAPK14LCKKDRCSF1RKIT | |
| SCHEMBL4502128 | 0.81 | MAPK14 (0.50) | MAPK14LCKKDRCSF1RRIPK2 | |
| SCHEMBL4509050 | 0.80 | RIPK2 (0.53) | MAPK14LCKKDRCSF1RRIPK2 | |
| SCHEMBL4516097 | 0.80 | MAPK14 (0.50) | MAPK14LCKKDRCSF1RKIT | |
| Gw820759X SCHEMBL3524287 | 0.79 | MAPK14 (1.00) | MAPK14LCKKDRCSF1RKIT | |
| SCHEMBL4502768 | 0.78 | RIPK2 (0.55) | MAPK14LCKKDRKITMAPK9 | |
| SCHEMBL4490466 | 0.78 | MAPK14 (0.60) | MAPK14LCKKDRCSF1RRIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286775-A1 | Bicyclic Derivatives as P38 Kinase Inhibitors | PALAU PHARMA, S.A. (ES) | 2009-11-19 | — | — | US | claimed |
| EP-1917241-A2 | BICYCLIC DERIVATIVES AS P38 KINASE INHIBITORS | Palau Pharma, S.A. (ES) | 2008-05-07 | — | — | EP | claimed |
| WO-2007000339-A1 | BICYCLIC DERIVATIVES AS P38 KINASE INHIBITORS | PALAU PHARMA, S.A. (ES) | 2007-01-04 | — | — | WO | claimed |
| US-20090286775-A1 | Bicyclic Derivatives as P38 Kinase Inhibitors | PALAU PHARMA, S.A. (ES) | 2009-11-19 | — | — | US | disclosed |
| EP-1917241-A2 | BICYCLIC DERIVATIVES AS P38 KINASE INHIBITORS | Palau Pharma, S.A. (ES) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007000339-A1 | BICYCLIC DERIVATIVES AS P38 KINASE INHIBITORS | PALAU PHARMA, S.A. (ES) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286775-A1 | Bicyclic Derivatives as P38 Kinase Inhibitors | MAPK1, MAPKAPK2, MAPKAPK3 | MAPK14 26/4885LCK 173/4885KDR 2279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.