SCHEMBL449233

SCHEMBL449233

S=C1[C]=CC=CC1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL449236 0.70
SCHEMBL1004372 0.70
SCHEMBL8050182 0.70
SCHEMBL5081191 0.65
SCHEMBL450690 0.65
SCHEMBL6359336 0.65
SCHEMBL28957997 0.58
SCHEMBL27290656 0.49
SCHEMBL28130575 0.49
SCHEMBL1030889 0.49

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673373-A1 BICYCLIC COMPOUNDS WITH PHARMACEUTICAL ACTIVITY SMITHKLINE BEECHAM PLC (GB) 1995-09-27 EP claimed
WO-1994013656-A1 BICYCLIC COMPOUNDS WITH PHARMACEUTICAL ACTIVITY SMITHKLINE BEECHAM PLC (GB) 1994-06-23 WO claimed
US-9963451-B2 Fused ring pyrimidine compound and pest control agent containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2018-05-08 US disclosed
US-9560848-B2 Method and compositions for biofouling deterrence CLEMSON UNIVERSITY (US) 2017-02-07 US disclosed
EP-2997824-A1 NOVEL HERBICIDES Syngenta Participations AG. (CH) 2016-03-23 EP disclosed
US-20150368249-A1 FUSED RING PYRIMIDINE COMPOUND AND PEST CONTROL AGENT CONTAINING THE SAME MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2015-12-24 US disclosed
EP-2375898-B1 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2015-09-16 EP disclosed
US-8889595-B2 Herbicides SYNGENTA PARTICIPATIONS AG (CH) 2014-11-18 US disclosed
US-20120065064-A1 NOVEL HERBICIDES SYNGENTA CROP PROTECTION LLC (US) 2012-03-15 US disclosed
US-20110123477-A1 METHOD AND COMPOSITIONS FOR BIOFOULING DETERRENCE NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2011-05-26 US disclosed
EP-2274384-A2 METHOD AND COMPOSITIONS FOR BIOFOULING DETERRENCE Clemson University (US) 2011-01-19 EP disclosed
WO-2009134303-A9 METHOD AND COMPOSITIONS FOR BIOFOULING DETERRENCE CLEMSON UNIVERSITY (US) 2010-02-18 WO disclosed
WO-2009134303-A2 METHOD AND COMPOSITIONS FOR BIOFOULING DETERRENCE CLEMSON UNIVERSITY (US) 2009-11-05 WO disclosed
US-5908860-A Bicyclic compounds with pharmaceutical activity SMITHKLINE BEECHAM PLC, (GB) 1999-06-01 US disclosed
EP-0673373-A1 BICYCLIC COMPOUNDS WITH PHARMACEUTICAL ACTIVITY SMITHKLINE BEECHAM PLC (GB) 1995-09-27 EP disclosed
WO-1994013656-A1 BICYCLIC COMPOUNDS WITH PHARMACEUTICAL ACTIVITY SMITHKLINE BEECHAM PLC (GB) 1994-06-23 WO disclosed