SCHEMBL449310

SCHEMBL449310

ClCC(Cl)OC(Cl)CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29584437 1.00
SCHEMBL21175342 0.79
SCHEMBL2559252 0.75 TP53 (0.41)
SCHEMBL3151349 0.75
SCHEMBL6152725 0.69
SCHEMBL11427675 0.69
SCHEMBL6152727 0.69
SCHEMBL11766274 0.69
SCHEMBL11427677 0.69
SCHEMBL468532 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6949560-B2 Imidazo-substituted compounds as p38 kinase inhibitors ROCHE PALO ALTO LLC (US) 2005-09-27 US claimed
US-20030232847-A1 Imidazo-substituted compounds as p38 kinase inhibitors ROCHE PALO ALTO LLC 2003-12-18 US claimed
JP-54100385-A None JP disclosed
US-20250333418-A1 PURINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF NOVO NORDISK AS (DK) 2025-10-30 US disclosed
EP-4608835-A1 PURINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF Novo Nordisk A/S (DK) 2025-09-03 EP disclosed
WO-2024116789-A1 LUBRICATING OIL COMPOSITION 出光興産株式会社 2024-06-06 WO disclosed
WO-2024080214-A1 METHOD FOR PRODUCING α-OLEFIN POLYMER 出光興産株式会社 2024-04-18 WO disclosed
CN-113316488-B Container and method for producing the same 美国富士电子材料股份有限公司 2024-03-12 CN disclosed
CN-115734817-A System and method for purifying solvent 富士胶片电子材料美国有限公司 2023-03-03 CN disclosed
CN-115697516-A System and method for purifying solvent 富士胶片电子材料美国有限公司 2023-02-03 CN disclosed
CN-112272585-B Chemical liquid manufacturing apparatus 美国富士电子材料股份有限公司 2022-09-13 CN disclosed
US-4363919-A Heterofulvalene geminal dithiolate compounds and their selenium and tellurium analogs and a method of fabricating the same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1982-12-14 US disclosed
US-4362662-A Heterofulvalene geminal dithiolate compounds and their selenium and tellurium analogs and a method of fabricating the same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1982-12-07 US disclosed
US-4312991-A Dithiobenzoate 4,5-dicyano-1,3-(dithiolidene-2-yl)methylene INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1982-01-26 US disclosed
EP-0020896-A1 A method of fabricating dithiafulven geminal dithiolate compounds and their selenium analogs International Business Machines Corporation (US) 1981-01-07 EP disclosed
JP-S54100385-A 5-FLUOROURACIL DERIVATIVE AND ITS PREPARATION MEIJI SEIKA KAISHA LTD 1979-08-08 JP disclosed
US-4148799-A Process for the preparation of 2-aryliminothiazoline solutions BAYER AKTIENGESELLSCHAFT (DE) 1979-04-10 US disclosed
US-4010176-A Isoxazole substituted nitroimidazoles MERCK & CO., INC. (US) 1977-03-01 US disclosed
US-RE28698-E Electrophotographic material containing sensitizers MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1976-01-27 US disclosed
US-3935200-A HERBICIDE BASF AKTIENGESELLSCHAFT (DT) 1976-01-27 US disclosed