Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 17/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385991 | 0.94 | S1PR1 (0.48) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL385789 | 0.91 | S1PR1 (0.46) | S1PR1S1PR3S1PR5S1PR4S1PR2 | |
| SCHEMBL386291 | 0.91 | S1PR1 (0.46) | S1PR1S1PR3S1PR5S1PR4S1PR2 | |
| SCHEMBL383769 | 0.91 | S1PR1 (0.42) | S1PR1S1PR3S1PR5S1PR4S1PR2 | |
| SCHEMBL384340 | 0.91 | S1PR1 (0.45) | S1PR1S1PR3S1PR5S1PR4S1PR2 | |
| SCHEMBL386827 | 0.91 | S1PR1 (0.49) | S1PR1S1PR3S1PR5S1PR4S1PR2 | |
| SCHEMBL385453 | 0.90 | S1PR1 (0.44) | S1PR1S1PR3S1PR5S1PR4S1PR2 | |
| SCHEMBL387152 | 0.90 | S1PR1 (0.42) | S1PR1S1PR3S1PR5S1PR4S1PR2 | |
| SCHEMBL386424 | 0.90 | S1PR1 (0.44) | S1PR1S1PR3S1PR5S1PR4S1PR2 | |
| SCHEMBL386681 | 0.89 | S1PR1 (0.40) | S1PR1S1PR3S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638551-B2 | Amino alcohol compounds or phosphonic acid derivatives thereof | SANKYO COMPANY, LIMITED (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20070142335-A1 | Amino alcohol compounds or phosphonic acid derivatives thereof | SANKYO COMPANY, LIMITED (JP) | 2007-06-21 | — | — | US | disclosed |
| US-7199150-B2 | Amino alcohol compounds | SANKYO COMPANY, LIMITED (JP) | 2007-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142335-A1 | Amino alcohol compounds or phosphonic acid derivatives thereof | HRH3, C3AR1, HRH4 | S1PR1 70/4885S1PR3 89/4885S1PR5 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.