SCHEMBL449384

SCHEMBL449384

C=CC(=O)OCCCCOC(=O)CCCC(=O)O

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.62
ALDH1A1 P00352 5/20 0.62
CYP3A4 P08684 2/20 0.62
HPGD P15428 1/20 0.52
TP53 P04637 3/20 0.47
HIF1A Q16665 3/20 0.47
HSD17B10 Q99714 1/20 0.47
NPC1 O15118 1/20 0.46
THRB P10828 2/20 0.44
SLC22A6 Q4U2R8 1/20 0.39
ABCC4 O15439 1/20 0.37
MAPT P10636 1/20 0.37
CASP6 P55212 1/20 0.36
DGKA P23743 1/20 0.36
HCAR2 Q8TDS4 2/20 0.36
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5945216 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29810451 0.96 TSHR (0.62) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5945197 0.96 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL12251535 0.95 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL10033426 0.95 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL19934811 0.95 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL15828343 0.95 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL17280885 0.95 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL19934818 0.95 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL153516 0.95 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130316137-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-11-28 US claimed
US-8530572-B2 Brightness enhancing film comprising nanocomposite structure having improved crack resistance 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-09-10 US claimed
US-20120264899-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M INNOVATIVE PROPERTIES COMPANY 2012-10-18 US claimed
EP-2118149-B1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M INNOVATIVE PROPERTIES CO (US) 2012-05-23 EP claimed
JP-2010519599-A 2010-06-03 JP claimed
US-20100033826-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M INNOVATIVE PROPERTIES COMPANY 2010-02-11 US claimed
EP-2118149-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M Innovative Properties Company (US) 2009-11-18 EP claimed
WO-2008121465-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-09 WO claimed
EP-0462670-B1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same JOHNSON & JOHNSON CLIN DIAG (US) 1996-08-21 EP claimed
EP-0462644-B1 Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use JOHNSON & JOHNSON CLIN DIAG (US) 1995-10-18 EP claimed
US-5155166-A Diagnostic kits for detecting antibodies or antigens; reacting active amine- or sulfhydryl-containing compound with quaternized carboxylic polymers EASTMAN KODAK COMPANY (US) 1992-10-13 US claimed
US-5147777-A Analysis, diagnosis EASTMAN KODAK COMPANY (US) 1992-09-15 US claimed
EP-0462670-A1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP claimed
EP-0462644-A1 Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP claimed
EP-2310884-B1 FLEXIBLE HIGH REFRACTIVE INDEX ANTIREFLECTIVE FILM 3M INNOVATIVE PROPERTIES CO (US) 2019-02-20 EP disclosed
US-9383482-B2 Antireflective films comprising microstructured surface 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-07-05 US disclosed
US-8951616-B2 Ester group containing liquid crystals for optical or electro optical devices ROLIC AG (CH) 2015-02-10 US disclosed
EP-0468585-A2 Biologically active reagent, analytical element and methods for use of the reagent Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-29 EP disclosed
EP-0462670-A1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP disclosed
EP-0462644-A1 Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP disclosed