⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16463758 | 0.93 | HTT (0.35) | — | |
| SCHEMBL363519 | 0.93 | HTT (0.35) | — | |
| SCHEMBL4495573 | 0.83 | HTT (0.50) | — | |
| SCHEMBL3563784 | 0.81 | — | — | |
| SCHEMBL4506413 | 0.78 | MEN1 (0.45) | — | |
| SCHEMBL362180 | 0.77 | HSD17B10 (0.31) | — | |
| SCHEMBL11331420 | 0.75 | HSD17B10 (0.36) | — | |
| SCHEMBL11331417 | 0.75 | HSD17B10 (0.36) | — | |
| SCHEMBL37658 | 0.74 | — | — | |
| SCHEMBL10493858 | 0.73 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655291-B1 | COMPOUNDS HAVING THROMBOPOIETIN RECEPTOR AGONISM | SHIONOGI & CO (JP) | 2016-08-03 | — | — | EP | disclosed |
| US-20090318513-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN RECEPTOR AGONISM | SHIONOGI & CO., LTD. | 2009-12-24 | — | — | US | disclosed |
| US-7601746-B2 | Compounds exhibiting thrombopoietin receptor agonism | SHIONOGI & CO., LTD. (JP) | 2009-10-13 | — | — | US | disclosed |
| EP-1957472-A1 | METHOD FOR PRODUCING IONIC LIQUIDS | BASF SE (DE) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007057403-A1 | METHOD FOR PRODUCING IONIC LIQUIDS | BASF SE (DE) | 2007-05-24 | — | — | WO | disclosed |
| US-20070043087-A1 | Such as 3-{2,6-difluoro-4-[4,5-dihydro-6-(3,3-dimethylbutyl)naphtho[1,2-d]thiazol-2-ylcabamoyl)phenyl]-2-methylacrylic acid | EDDINGPHARM (HONG KONG) COMPANY LIMITED (CN) | 2007-02-22 | — | — | US | disclosed |
| EP-1655291-A1 | COMPOUNDS HAVING THROMBOPOIETIN RECEPTOR AGONISM | SHIONOGI & CO., LTD. (JP) | 2006-05-10 | — | — | EP | disclosed |