Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.44 |
| ▸ | IDH1 | O75874 | 5/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4077526 | 0.84 | PTPN1 (0.37) | ARIDH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4075016 | 0.82 | AR (0.43) | ARIDH1PDE3BPDE3AMEN1 | |
| SCHEMBL4075653 | 0.81 | AR (0.55) | ARIDH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4076674 | 0.81 | MAPT (0.52) | ARNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4084485 | 0.81 | NPC1 (0.41) | ARIDH1NPC1RAB9AMEN1 | |
| SCHEMBL4089532 | 0.80 | ABL1 (0.47) | ARIDH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4077279 | 0.80 | IDH1 (0.37) | ARIDH1NPC1RAB9AMEN1 | |
| SCHEMBL4077609 | 0.78 | MAPT (0.52) | ARIDH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4075308 | 0.78 | MEN1 (0.50) | ARNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4075167 | 0.77 | ABL1 (0.47) | ARIDH1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618990-B2 | 4-[2-(4,4-Dimethyl-2-thioxo-1,3-oxazolidin-3-yl)-1,3-thiazol-4-yl]benzonitrile; progesterone receptor (PR); contraception, treating or preventing fibroids, endometriosis, dysfunctional bleeding, uterine leiomyomata, polycystic ovary syndrome, or hormone-dependent carcinomas, hormone replacement therapy | WYETH (US) | 2009-11-17 | — | — | US | claimed |