SCHEMBL449509

SCHEMBL449509

[CH]1[CH]CC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6862011 0.88
SCHEMBL65096 0.73
SCHEMBL1112686 0.70
SCHEMBL1113117 0.70
SCHEMBL1541394 0.70
SCHEMBL1113115 0.70
SCHEMBL1112682 0.70
SCHEMBL1541370 0.70
SCHEMBL1540769 0.67
SCHEMBL1114039 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11981703-B2 Polynucleotide constructs SIRIUS THERAPEUTICS, INC. (US) 2024-05-14 US disclosed
EP-4341241-A1 CONTINUOUS FLOW PROCESS FOR PRODUCTION OF CATIONIC LIPIDS Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2024-03-27 EP disclosed
WO-2023250427-A2 FORMULATIONS FOR MODULATING MYC EXPRESSION FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2023-12-28 WO disclosed
WO-2023250429-A2 COMBINATION THERAPIES COMPRISING MYC MODULATION FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2023-12-28 WO disclosed
US-20230399423-A1 POLYMERIC DISINFECTANTS AND USES THEREOF TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2023-12-14 US disclosed
US-20230321083-A1 Inhibitors of GPR174 and Uses Thereof OMEROS CORP (US) 2023-10-12 US disclosed
US-20230285556-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER OMEROS CORPORATION 2023-09-14 US disclosed
US-20230242567-A1 CHIRAL PHOSPHORAMIDITE AUXILIARIES AND METHODS OF THEIR USE SIRIUS THERAPEUTICS, INC. 2023-08-03 US disclosed
EP-4183770-A1 CONTINUOUS FLOW PROCESS FOR PRODUCTION OF CATIONIC LIPIDS Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-24 EP disclosed
US-11597744-B2 Chiral phosphoramidite auxiliaries and methods of their use SIRIUS THERAPEUTICS, INC. (US) 2023-03-07 US disclosed
WO-2005011721-A2 USE OF A PAK INHIBITOR FOR THE TREATMENT OF A JOINT DISEASE SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2005-02-10 WO disclosed
US-20050014870-A1 Resin composition SONY CORPORATION (JP) 2005-01-20 US disclosed
EP-1498133-A1 Use of a pak inhibitor for the treatment of a joint disease Aventis Pharma Deutschland GmbH (DE) 2005-01-19 EP disclosed
US-6794530-B1 1,4-ADDITION OF MONOHYDRIC OR POLYHYDRIC ALCOHOLS TO ALPHA , BETA -UNSATURATED NITRILES BASF AKTIENGESELLSCHAFT (DE) 2004-09-21 US disclosed
WO-2004056747-A1 DHODH-INHIBITORS AND METHOD FOR THEIR IDENTIFICATION 4SC AG (DE) 2004-07-08 WO disclosed
EP-0934925-B1 Process for the preparation of beta-alkoxy nitriles BASF AG (DE) 2002-09-25 EP disclosed
EP-0934925-A1 Process for the preparation of beta-alkoxy nitriles BASF AKTIENGESELLSCHAFT (DE) 1999-08-11 EP disclosed
EP-0594292-B1 Polyols and their use for the manufacture of polyurethanes. ICI PLC (GB) 1998-01-21 EP disclosed
US-5710232-A Poly(ester-amide) polyols IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1998-01-20 US disclosed
EP-0594292-A1 Novel polyols IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-04-27 EP disclosed