Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.64 |
| ▸ | LCK | P06239 | 1/20 | 0.64 |
| ▸ | FYN | P06241 | 1/20 | 0.64 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6662900 | 1.00 | FFAR3 (0.64) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL31377001 | 1.00 | FFAR3 (0.64) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL10946765 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL870378 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL27792206 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL7155336 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL9098767 | 0.87 | FFAR3 (0.58) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL1025735 | 0.87 | — | — | |
| Acetic Acid SCHEMBL3634629 | 0.87 | FFAR3 (0.58) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL1140278 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490682-A | Antimicrobial peptides and methods of use thereof | 豪夫迈·罗氏有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-111529558-A | Application of acanthopanax gracilistylus leaf total extract in preparation of hypoglycemic drugs | 湖南中医药大学 | 2020-08-14 | — | — | CN | disclosed |
| CN-111419852-A | Application of 3 α, 11 α -dihydroxy-lupin-20 (29) -alkene-28-acid in preparation of hypoglycemic drugs | 湖南中医药大学 | 2020-07-17 | — | — | CN | disclosed |
| US-9671367-B2 | Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis | APPLIED BIOSYSTEMS, LLC (US) | 2017-06-06 | — | — | US | disclosed |
| EP-3075385-A1 | AMIDE BASED GLUCAGON SUPERFAMILY PEPTIDE PRODRUGS | Indiana University Research and Technology Corporation (US) | 2016-10-05 | — | — | EP | disclosed |
| US-9173969-B2 | Biomaterial for wound healing | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2015-11-03 | — | — | US | disclosed |
| CN-102459325-B | Gastrostatin receptor activated glucagon compounds | UNIV INDIANA RES & TECH CORP | 2015-03-25 | — | — | CN | disclosed |
| US-8969288-B2 | Amide based glucagon and superfamily peptide prodrugs | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-03-03 | — | — | US | disclosed |
| US-20140209461-A1 | Poly and Copoly(N-vinylamide)s and Their Use In Capillary Electrophoresis | APPLIED BIOSYSTEMS, LLC (US) | 2014-07-31 | — | — | US | disclosed |
| US-8778872-B2 | Amide based glucagon superfamily peptide prodrugs | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2014-07-15 | — | — | US | disclosed |
| US-20060022367-A1 | Display element and manufacturing method thereof | OJI PAPER CO., LTD. (JP) | 2006-02-02 | — | — | US | disclosed |
| EP-1555569-A1 | DISPLAY ELEMENT AND MANUFACTURING METHOD THEREOF | Oji Paper Co., Ltd. (JP) | 2005-07-20 | — | — | EP | disclosed |
| EP-0733945-B1 | Composition for developing an exposed photographic product having improved stability in air | EASTMAN KODAK CO (US) | 2002-10-23 | — | — | EP | disclosed |
| US-5686232-A | Composition for developing an exposed photographic product having improved stability in air | EASTMAN KODAK COMPANY (US) | 1997-11-11 | — | — | US | disclosed |
| US-5656415-A | Composition for developing an exposed photographic product having improved stability in air | EASTMAN KODAK COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0733945-A1 | Composition for developing an exposed photographic product having improved stability in air | KODAK-PATHE (FR) | 1996-09-25 | — | — | EP | disclosed |
| EP-0732620-A1 | Composition for developing an exposed photographic product having improved biodegradability | KODAK-PATHE (FR) | 1996-09-18 | — | — | EP | disclosed |
| EP-0265186-A2 | Anticalculus compositions | THE PROCTER & GAMBLE COMPANY (US) | 1988-04-27 | — | — | EP | disclosed |
| US-4452892-A | GELLING AN ACRYLIC MONOMER AND THICKENER; RHEOLOGY | UNITED KINGDOM ATOMIC ENERGY AUTHORITY (GB) | 1984-06-05 | — | — | US | disclosed |
| EP-0048109-A2 | Improvements in or relating to composite materials | UNITED KINGDOM ATOMIC ENERGY AUTHORITY (GB) | 1982-03-24 | — | — | EP | disclosed |