SCHEMBL4495461

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6387515	0.86	HDAC1 (0.49)	CA12CA1CA9HDAC1HDAC3
	SCHEMBL6387415	0.85	HDAC1 (0.51)	CA12CA1CA9HDAC1HDAC3
	SCHEMBL6076459	0.84	HDAC1 (0.65)	CA12CA1CA9HDAC1HDAC3
	SCHEMBL6387635	0.83	HDAC1 (0.48)	CA12CA1CA9HDAC1HDAC3
	SCHEMBL6385514	0.82	HDAC1 (0.50)	CA12CA1CA9HDAC1HDAC3
	SCHEMBL6384160	0.82	CA12 (0.45)	CA12CA1CA9HDAC1HDAC3
	SCHEMBL4493067	0.81	HDAC3 (0.57)	CA12CA1CA9HDAC1HDAC3
	SCHEMBL4473775	0.79	HDAC3 (0.64)	HDAC1HDAC3HDAC2NCOR2MAPK1
	SCHEMBL6383174	0.79	CA12 (0.44)	CA12CA1CA9HDAC1HDAC3
	SCHEMBL8401704	0.78	HDAC1 (0.89)	HDAC1HDAC3HDAC2NCOR2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.