Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Emedastine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Emedastine SCHEMBL449580 | 1.00 | POLB (0.62) | POLB | |
| Emedastine SCHEMBL29846167 | 1.00 | POLB (0.62) | POLB | |
| Emedastine SCHEMBL41384 | 1.00 | POLB (0.62) | POLB | |
| Emedastine SCHEMBL41386 | 1.00 | POLB (0.62) | POLB | |
| Emedastine SCHEMBL1649085 | 1.00 | POLB (0.62) | POLB | |
| Emedastine SCHEMBL41385 | 1.00 | POLB (0.62) | POLB | |
| Fumaric Acid SCHEMBL10920208 | 0.93 | POLB (0.63) | POLB | |
| Fumaric Acid SCHEMBL10920204 | 0.93 | POLB (0.63) | POLB | |
| Emedastine SCHEMBL29770 | 0.91 | — | — | |
| Emedastine SCHEMBL29493445 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 463 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122031382-A | Emerastine fumarate eye drops and preparation method thereof | 江苏远恒药业有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-120131543-A | Emerastine fumarate eye drops and preparation method thereof | 石家庄四药有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-119139256-B | Emedastine fumarate preparation and preparation method thereof | 安徽瑞旗药业有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-119241510-A | Preparation method of emedastine fumarate | 南京唯创远医药科技有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-119139256-A | Emedastine fumarate preparation and preparation method thereof | 安徽瑞旗药业有限公司 | 2024-12-17 | — | — | CN | claimed |
| CN-118903147-A | Emedastine fumarate composition and preparation method thereof | 湖南普道医药技术有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-118812440-A | Method for continuously preparing intermediate 1- (2-ethoxyethyl) -2- (4-methyl-1, 4-homopiperazin-1-yl) -1H- [ d ] -benzimidazole | 南京恒道医药科技股份有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-118557551-A | Emerastine fumarate sustained-release capsule and preparation method thereof | 四川德峰药业有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-107735401-B | Substituted dihydropyrrolopyrazole derivatives | 宇部兴产株式会社 | 2021-08-31 | — | — | CN | claimed |
| CN-107875119-B | Emedastine fumarate aqueous pharmaceutical composition and preparation method thereof | 山东绅联药业有限公司 | 2021-03-12 | — | — | CN | claimed |
| EP-2043613-A1 | SOLID FORM | FMC CORPORATION (US) | 2009-04-08 | — | — | EP | claimed |
| US-20080311162-A1 | Solid form | FMC CORPORATION | 2008-12-18 | — | — | US | claimed |
| US-20080286343-A1 | Solid form | FMC CORPORATION | 2008-11-20 | — | — | US | claimed |
| WO-2008140460-A1 | SOLID FORM | FMC CORPORATION (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140461-A1 | SOLID FORM | FMC CORPORATION (US) | 2008-11-20 | — | — | WO | claimed |
| US-20080286344-A1 | Solid form | FMC CORPORATION | 2008-11-20 | — | — | US | claimed |
| WO-2008008120-A1 | SOLID FORM | FMC CORPORATION (US) | 2008-01-17 | — | — | WO | claimed |
| US-20080014228-A1 | Solid form | FMC CORPORATION | 2008-01-17 | — | — | US | claimed |
| CN-1658888-A | Quaternised ammonium cyclodextrin compounds | NOVARTIS AG (CH) | 2005-08-24 | — | — | CN | claimed |
| CN-1483478-A | Eye preparation formula adapted for therapentic medicine | 无锡杰西医药科技有限公司 | 2004-03-24 | — | — | CN | claimed |